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ANKRD24 ankyrin repeat domain 24 [ Homo sapiens (human) ]

Gene ID: 170961, updated on 26-Oct-2022

Summary

Official Symbol
ANKRD24provided by HGNC
Official Full Name
ankyrin repeat domain 24provided by HGNC
Primary source
HGNC:HGNC:29424
See related
Ensembl:ENSG00000089847 AllianceGenome:HGNC:29424
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Broad expression in brain (RPKM 3.5), testis (RPKM 2.5) and 16 other tissues See more
Orthologs
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Genomic context

See ANKRD24 in Genome Data Viewer
Location:
19p13.3
Exon count:
31
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (4182689..4224814)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (4165992..4208117)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (4182686..4224811)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene cAMP responsive element binding protein 3 like 3 Neighboring gene sirtuin 6 Neighboring gene Epstein-Barr virus induced 3 Neighboring gene YJU2 splicing factor homolog

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • KIAA1981

General protein information

Preferred Names
ankyrin repeat domain-containing protein 24

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001393552.1NP_001380481.1  ankyrin repeat domain-containing protein 24 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (a).
    Source sequence(s)
    AC005578, AC006930
    Conserved Domains (5) summary
    COG0666
    Location:110246
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    COG1196
    Location:3311113
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:7651109
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00045
    Location:147187
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:223275
    Ank_4; Ankyrin repeats (many copies)
  2. NM_001393553.1NP_001380482.1  ankyrin repeat domain-containing protein 24 isoform b

    Status: VALIDATED

    Source sequence(s)
    AC005578, AC006930
    Consensus CDS
    CCDS45925.1
    UniProtKB/Swiss-Prot
    O95781
    Conserved Domains (3) summary
    TIGR02168
    Location:3241100
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00045
    Location:115145
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:119211
    Ank_2; Ankyrin repeats (3 copies)
  3. NM_001393555.1NP_001380484.1  ankyrin repeat domain-containing protein 24 isoform c

    Status: VALIDATED

    Source sequence(s)
    AC005578, AC006930
    Conserved Domains (5) summary
    COG0666
    Location:81208
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    COG1196
    Location:2931075
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:7271071
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00045
    Location:86116
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:185237
    Ank_4; Ankyrin repeats (many copies)
  4. NM_001393556.1NP_001380485.1  ankyrin repeat domain-containing protein 24 isoform d

    Status: VALIDATED

    Source sequence(s)
    AC005578, AC006930
    Related
    ENSP00000262970.4, ENST00000262970.9
    Conserved Domains (5) summary
    COG0666
    Location:82209
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    COG1196
    Location:2941076
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:7281072
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00045
    Location:87117
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:186238
    Ank_4; Ankyrin repeats (many copies)
  5. NM_001393557.1NP_001380486.1  ankyrin repeat domain-containing protein 24 isoform e

    Status: VALIDATED

    Source sequence(s)
    AC005578, AC006930
    Conserved Domains (5) summary
    COG0666
    Location:94221
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    COG1196
    Location:3061088
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:7401084
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00045
    Location:99129
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:198250
    Ank_4; Ankyrin repeats (many copies)
  6. NM_001393985.1NP_001380914.1  ankyrin repeat domain-containing protein 24 isoform b

    Status: VALIDATED

    Source sequence(s)
    AC005578, AC006930
    Consensus CDS
    CCDS45925.1
    UniProtKB/Swiss-Prot
    O95781
    Related
    ENSP00000321731.4, ENST00000318934.9
    Conserved Domains (3) summary
    TIGR02168
    Location:3241100
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00045
    Location:115145
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:119211
    Ank_2; Ankyrin repeats (3 copies)
  7. NM_133475.1NP_597732.1  ankyrin repeat domain-containing protein 24 isoform b

    See identical proteins and their annotated locations for NP_597732.1

    Status: VALIDATED

    Source sequence(s)
    AB075861, AC005578, BI914435, BX117359, BX359277, CN286920
    Consensus CDS
    CCDS45925.1
    UniProtKB/Swiss-Prot
    O95781, Q8TF21
    Related
    ENSP00000471252.1, ENST00000600132.5
    Conserved Domains (3) summary
    TIGR02168
    Location:3241100
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00045
    Location:115145
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:119211
    Ank_2; Ankyrin repeats (3 copies)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    4182689..4224814
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011527761.2XP_011526063.1  ankyrin repeat domain-containing protein 24 isoform X4

    See identical proteins and their annotated locations for XP_011526063.1

    Conserved Domains (7) summary
    cd00204
    Location:115243
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam04094
    Location:567981
    DUF390; Protein of unknown function (DUF390)
    pfam12796
    Location:119253
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:147187
    ANK; ANK repeat [structural motif]
    cl02219
    Location:10931170
    Bap31; B-cell receptor-associated protein 31-like
    cl23720
    Location:10471135
    RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
    cl23750
    Location:864969
    vATP-synt_E; ATP synthase (E/31 kDa) subunit
  2. XM_011527756.3XP_011526058.2  ankyrin repeat domain-containing protein 24 isoform X2

  3. XM_011527758.3XP_011526060.2  ankyrin repeat domain-containing protein 24 isoform X3

  4. XM_017026438.2XP_016881927.1  ankyrin repeat domain-containing protein 24 isoform X4

    Conserved Domains (7) summary
    cd00204
    Location:115243
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam04094
    Location:567981
    DUF390; Protein of unknown function (DUF390)
    pfam12796
    Location:119253
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:147187
    ANK; ANK repeat [structural motif]
    cl02219
    Location:10931170
    Bap31; B-cell receptor-associated protein 31-like
    cl23720
    Location:10471135
    RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
    cl23750
    Location:864969
    vATP-synt_E; ATP synthase (E/31 kDa) subunit
  5. XM_024451405.2XP_024307173.2  ankyrin repeat domain-containing protein 24 isoform X1

  6. XM_011527764.4XP_011526066.2  ankyrin repeat domain-containing protein 24 isoform X5

  7. XM_011527765.3XP_011526067.1  ankyrin repeat domain-containing protein 24 isoform X6

    Conserved Domains (7) summary
    cd00204
    Location:87215
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam04094
    Location:539953
    DUF390; Protein of unknown function (DUF390)
    pfam07989
    Location:10981150
    Cnn_1N; Centrosomin N-terminal motif 1
    pfam12796
    Location:91225
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:119159
    ANK; ANK repeat [structural motif]
    cl23720
    Location:10191107
    RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
    cl23750
    Location:836941
    vATP-synt_E; ATP synthase (E/31 kDa) subunit
  8. XM_047438378.1XP_047294334.1  ankyrin repeat domain-containing protein 24 isoform X7

  9. XM_017026441.2XP_016881930.1  ankyrin repeat domain-containing protein 24 isoform X8

  10. XM_011527768.3XP_011526070.1  ankyrin repeat domain-containing protein 24 isoform X9

    Conserved Domains (1) summary
    cl02219
    Location:674751
    Bap31; B-cell receptor-associated protein 31-like

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    4165992..4208117
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)