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Rfxap regulatory factor X-associated protein [ Mus musculus (house mouse) ]

Gene ID: 170767, updated on 14-May-2024

Summary

Official Symbol
Rfxapprovided by MGI
Official Full Name
regulatory factor X-associated proteinprovided by MGI
Primary source
MGI:MGI:2180854
See related
Ensembl:ENSMUSG00000036615 AllianceGenome:MGI:2180854
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
5730495K23Rik
Summary
Enables DNA binding activity. Acts upstream of or within positive regulation of transcription, DNA-templated. Located in nucleus. Is expressed in 2nd branchial arch; embryo; limb; and limb mesenchyme. Human ortholog(s) of this gene implicated in MHC class II deficiency. Orthologous to human RFXAP (regulatory factor X associated protein). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary adult (RPKM 17.3), CNS E18 (RPKM 14.0) and 28 other tissues See more
Orthologs
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Genomic context

See Rfxap in Genome Data Viewer
Location:
3 C; 3 25.69 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (54710536..54715212, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (54803115..54807791, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene ALG5 dolichyl-phosphate beta-glucosyltransferase Neighboring gene SMAD family member 9 Neighboring gene STARR-seq mESC enhancer starr_07686 Neighboring gene splicing factor, arginine/serine-rich 10 pseudogene Neighboring gene STARR-seq mESC enhancer starr_07687 Neighboring gene serine rich and transmembrane domain containing 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
regulatory factor X-associated protein
Names
RFX-associated protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_133231.2NP_573494.1  regulatory factor X-associated protein

    See identical proteins and their annotated locations for NP_573494.1

    Status: VALIDATED

    Source sequence(s)
    AF335512, AI607302, AK087489, AW826111, BQ830204, BX519947
    Consensus CDS
    CCDS50907.1
    UniProtKB/Swiss-Prot
    Q8VCG9, Q91Y54
    UniProtKB/TrEMBL
    F7DBT7
    Related
    ENSMUSP00000040917.5, ENSMUST00000044373.6
    Conserved Domains (1) summary
    pfam15289
    Location:100202
    RFXA_RFXANK_bdg; Regulatory factor X-associated C-terminal binding domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    54710536..54715212 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)