Zfp87 zinc finger protein 87 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Zfp87provided by MGI
Official Full Name: zinc finger protein 87provided by MGI
Primary source: MGI:MGI:107768
See related: Ensembl:ENSMUSG00000097333 AllianceGenome:MGI:107768
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: KRAB4; Mzf22; Zfp72; 2210039O17Rik; 4631412O18Rik
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including genitourinary system; lung; pharyngo-tympanic tube; retina nuclear layer; and thymus primordium. Orthologous to several human genes including ZNF429 (zinc finger protein 429). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in CNS E14 (RPKM 4.1), CNS E11.5 (RPKM 4.1) and 27 other tissues See more
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 13 B3; 13 34.54 cM

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
109	current	GRCm39 (GCF_000001635.27)	13	NC_000079.7 (67663900..67674350, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	13	NC_000079.6 (67515781..67526231, complement)

Chromosome 13 - NC_000079.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: zinc finger protein 87

Names: KRAB zinc finger protein (Mzf22); zinc finger protein 72

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_133228.3 → NP_573491.2 zinc finger protein 87

See identical proteins and their annotated locations for NP_573491.2

Status: VALIDATED

Source sequence(s)

CT573016

Consensus CDS

CCDS59588.1

UniProtKB/TrEMBL

Q8K2A4

Related

ENSMUSP00000138087.2, ENSMUST00000181767.8

Conserved Domains (5) summary

smart00349
Location:5 → 65

KRAB; krueppel associated box

COG5048
Location:107 → 472

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:223 → 243

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam01352
Location:5 → 44

KRAB; KRAB box

pfam13465
Location:123 → 148

zf-H2C2_2; Zinc-finger double domain