U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Acbd3 acyl-Coenzyme A binding domain containing 3 [ Mus musculus (house mouse) ]

Gene ID: 170760, updated on 12-May-2024

Summary

Official Symbol
Acbd3provided by MGI
Official Full Name
acyl-Coenzyme A binding domain containing 3provided by MGI
Primary source
MGI:MGI:2181074
See related
Ensembl:ENSMUSG00000026499 AllianceGenome:MGI:2181074
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Pap7; 60kDa; GCP60; GOLPH1; Gocap1; D1Ertd10e; 8430407O11Rik
Summary
Predicted to enable protein kinase A regulatory subunit binding activity. Predicted to act upstream of or within steroid biosynthetic process. Predicted to be located in Golgi apparatus. Predicted to be active in Golgi membrane. Is expressed in brain; genitourinary system; gut; and lung. Orthologous to human ACBD3 (acyl-CoA binding domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in placenta adult (RPKM 17.7), limb E14.5 (RPKM 13.6) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Acbd3 in Genome Data Viewer
Location:
1 H4; 1 84.46 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (180553608..180581769)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (180726043..180754204)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene lin-9 DREAM MuvB core complex component Neighboring gene Mix paired-like homeobox Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:182694146-182694255 Neighboring gene predicted gene, 38293 Neighboring gene RIKEN cDNA 2900024J01 gene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (2) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables fatty-acyl-CoA binding IEA
Inferred from Electronic Annotation
more info
 
enables protein kinase A regulatory subunit binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within steroid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in Golgi membrane ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Golgi resident protein GCP60
Names
PBR associated protein
PBR- and PKA-associated protein 7
acyl-CoA-binding domain-containing protein 3
golgi complex associated protein 1, 60 kDa
golgi complex-associated protein 1
golgi phosphoprotein 1
peripheral benzodiazepine receptor-associated protein PAP7
peripherial benzodiazepine receptor associated protein

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_133225.3NP_573488.2  Golgi resident protein GCP60

    See identical proteins and their annotated locations for NP_573488.2

    Status: VALIDATED

    Source sequence(s)
    AK030371, BC060602, BU756506
    Consensus CDS
    CCDS15572.1
    UniProtKB/Swiss-Prot
    O35371, Q8BMP6
    UniProtKB/TrEMBL
    A0A0R4J079
    Related
    ENSMUSP00000027780.5, ENSMUST00000027780.6
    Conserved Domains (2) summary
    pfam00887
    Location:81167
    ACBP; Acyl CoA binding protein
    pfam13897
    Location:394524
    GOLD_2; Golgi-dynamics membrane-trafficking

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    180553608..180581769
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)