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Trhr2 thyrotropin releasing hormone receptor 2 [ Mus musculus (house mouse) ]

Gene ID: 170732, updated on 14-Aug-2019

Summary

Official Symbol
Trhr2provided by MGI
Official Full Name
thyrotropin releasing hormone receptor 2provided by MGI
Primary source
MGI:MGI:2177284
See related
Ensembl:ENSMUSG00000039079
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
TRH-R2
Expression
Biased expression in cortex adult (RPKM 1.2), frontal lobe adult (RPKM 1.1) and 7 other tissues See more

Genomic context

See Trhr2 in Genome Data Viewer
Location:
8; 8 E1
Exon count:
4
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (122356065..122363294, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (124880867..124884646, complement)

Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene zinc finger protein, multitype 1 Neighboring gene Zfpm1R12 erythroid cis-regulatory module Neighboring gene predicted gene, 46056 Neighboring gene predicted gene, 39270 Neighboring gene zinc finger CCCH-type containing 18 Neighboring gene interleukin 17C

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from BioSystems

  • Calcium signaling pathway, organism-specific biosystem (from KEGG)
    Calcium signaling pathway, organism-specific biosystemCa2+ that enters the cell from the outside is a principal source of signal Ca2+. Entry of Ca2+ is driven by the presence of a large electrochemical gradient across the plasma membrane. Cells use this...
  • Calcium signaling pathway, conserved biosystem (from KEGG)
    Calcium signaling pathway, conserved biosystemCa2+ that enters the cell from the outside is a principal source of signal Ca2+. Entry of Ca2+ is driven by the presence of a large electrochemical gradient across the plasma membrane. Cells use this...
  • GPCRs, Class A Rhodopsin-like, organism-specific biosystem (from WikiPathways)
    GPCRs, Class A Rhodopsin-like, organism-specific biosystemThis pathway was created using the GPCRDB (Horn et al., 1998), http://www.gpcr.org/7tm/ (originally at http://www.cmbi.kun.nl/7tm/). The groupings are based on the GPCR phylogenetic tree available fr...
  • GPCRs, Other, organism-specific biosystem (from WikiPathways)
    GPCRs, Other, organism-specific biosystemThis pathway was created using the GPCRDB (Horn et al., 1998), http://www.cmbi.kun.nl/7tm/. The groupings are based on the GPCR phylogenetic tree available from the GPCRDB and the training sets used ...
  • Neuroactive ligand-receptor interaction, organism-specific biosystem (from KEGG)
    Neuroactive ligand-receptor interaction, organism-specific biosystem
    Neuroactive ligand-receptor interaction
  • Neuroactive ligand-receptor interaction, conserved biosystem (from KEGG)
    Neuroactive ligand-receptor interaction, conserved biosystem
    Neuroactive ligand-receptor interaction

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
thyrotropin-releasing hormone receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
thyrotropin-releasing hormone receptor activity ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
integral component of plasma membrane ISA
Inferred from Sequence Alignment
more info
PubMed 
neuronal cell body ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
thyrotropin releasing hormone receptor 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_133202.3NP_573465.1  thyrotropin releasing hormone receptor 2

    See identical proteins and their annotated locations for NP_573465.1

    Status: VALIDATED

    Source sequence(s)
    AL591003
    Consensus CDS
    CCDS22734.1
    UniProtKB/TrEMBL
    Q9ERT2
    Conserved Domains (2) summary
    pfam00001
    Location:39308
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:35161
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000074.6 Reference GRCm38.p6 C57BL/6J

    Range
    122356065..122363294 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030243315.1XP_030099175.1  thyrotropin releasing hormone receptor 2 isoform X2

  2. XM_030243314.1XP_030099174.1  thyrotropin releasing hormone receptor 2 isoform X1

    Related
    ENSMUSP00000042575.1, ENSMUST00000044123.1
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