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Fgf3 fibroblast growth factor 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 170633, updated on 21-Jul-2018

Summary

Official Symbol
Fgf3provided by RGD
Official Full Name
fibroblast growth factor 3provided by RGD
Primary source
RGD:620126
See related
Ensembl:ENSRNOG00000020888
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Int2
Summary
member of the fibroblast growth factor (FGF) family; implicated in activities including embryonic development, cell growth, morphogenesis, tissue growth, and tumor growth and invasion [RGD, Feb 2006]
Expression
Low expression observed in reference dataset See more
Orthologs

Genomic context

See Fgf3 in Genome Data Viewer
Location:
1q42
Exon count:
3
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (218003018..218006942)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 1 NC_005100.3 (224872403..224876327)

Chromosome 1 - NC_005100.4Genomic Context describing neighboring genes Neighboring gene anoctamin 1 Neighboring gene uncharacterized LOC108349677 Neighboring gene uncharacterized LOC108349678 Neighboring gene fibroblast growth factor 4

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
fibroblast growth factor receptor binding IEA
Inferred from Electronic Annotation
more info
 
growth factor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
fibroblast growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
fibroblast growth factor receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
negative regulation of cardiac muscle tissue development IEA
Inferred from Electronic Annotation
more info
 
negative regulation of cardiac muscle tissue development ISO
Inferred from Sequence Orthology
more info
 
organ induction ISO
Inferred from Sequence Orthology
more info
 
otic vesicle formation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cell proliferation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of cell proliferation ISO
Inferred from Sequence Orthology
more info
 
post-anal tail morphogenesis ISO
Inferred from Sequence Orthology
more info
 
regulation of signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 
semicircular canal morphogenesis ISO
Inferred from Sequence Orthology
more info
 
thymus development ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
extracellular region IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
fibroblast growth factor 3
Names
interacting gene 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_130817.1NP_570830.1  fibroblast growth factor 3 precursor

    See identical proteins and their annotated locations for NP_570830.1

    Status: PROVISIONAL

    Source sequence(s)
    AB079262
    UniProtKB/TrEMBL
    Q8R5L9
    Related
    ENSRNOP00000028343.3, ENSRNOT00000028343.4
    Conserved Domains (1) summary
    smart00442
    Location:44181
    FGF; Acidic and basic fibroblast growth factor family

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005100.4 Reference Rnor_6.0 Primary Assembly

    Range
    218003018..218006942
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000069.1 Alternate Rn_Celera

    Range
    197559343..197563267
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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