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Klrb1c killer cell lectin-like receptor subfamily B member 1C [ Mus musculus (house mouse) ]

Gene ID: 17059, updated on 7-Sep-2021

Summary

Official Symbol
Klrb1cprovided by MGI
Official Full Name
killer cell lectin-like receptor subfamily B member 1Cprovided by MGI
Primary source
MGI:MGI:107538
See related
Ensembl:ENSMUSG00000030325
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Nk; Ly5; NK-; NKR; Nk1; Ly-5; Ly55; Ly59; NKR-; Nk-1; Nk1.; Nkrp; CD161; Ly-59; Ly55c; NK-1.; NK1.1; NKRP1; Nk1.2; Klrb1b; NK-RP1; Nk-1.2; Nkrp1b; Nkrp1c; ly-55c; NKRP140; AI462337; NKR-P1.9
Expression
Biased expression in genital fat pad adult (RPKM 16.6) and spleen adult (RPKM 2.1) See more
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Genomic context

See Klrb1c in Genome Data Viewer
Location:
6 F3; 6 63.09 cM
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (128755448..128765604, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (128778485..128788641, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (128728503..128738659, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene C-type lectin domain family 2, member h Neighboring gene killer cell lectin-like receptor subfamily B member 1 Neighboring gene predicted gene, 34755 Neighboring gene killer cell lectin-like receptor subfamily B member 1B

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables signaling receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in cell surface IDA
Inferred from Direct Assay
more info
PubMed 
located_in external side of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in integral component of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
killer cell lectin-like receptor subfamily B member 1C
Names
CD161 antigen-like family member C
NKR-P1 40
NKR-P1B
killer cell lectin-like receptor subfamily A member 1C
lymphocyte antigen 55 complex, locus C
lymphocyte antigen 55c
lymphocyte antigen 59
natural killer cell receptor protein NKR-P1C
natural killer cell receptor-P1
natural killer cell surface protein P1-40
natural killer cell-associated antigen 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001159904.1NP_001153376.1  killer cell lectin-like receptor subfamily B member 1C isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC102693, AK079743, M77678
    Consensus CDS
    CCDS51919.1
    UniProtKB/Swiss-Prot
    P27814
    UniProtKB/TrEMBL
    G3UZI0
    Related
    ENSMUSP00000134504.2, ENSMUST00000174404.8
    Conserved Domains (2) summary
    cd03593
    Location:142260
    CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
    PHA03097
    Location:89258
    PHA03097; C-type lectin-like protein; Provisional
  2. NM_008527.2NP_032553.2  killer cell lectin-like receptor subfamily B member 1C isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.
    Source sequence(s)
    AC102693, AK079743, M77678
    Consensus CDS
    CCDS39654.2
    UniProtKB/Swiss-Prot
    P27814
    UniProtKB/TrEMBL
    E9Q3U6
    Related
    ENSMUSP00000127297.3, ENSMUST00000167691.9
    Conserved Domains (2) summary
    cd03593
    Location:139257
    CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
    PHA03097
    Location:89255
    PHA03097; C-type lectin-like protein; Provisional

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    128755448..128765604 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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