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Stard5 StAR related lipid transfer domain containing 5 [ Mus musculus (house mouse) ]

Gene ID: 170460, updated on 4-May-2024

Summary

Official Symbol
Stard5provided by MGI
Official Full Name
StAR related lipid transfer domain containing 5provided by MGI
Primary source
MGI:MGI:2156765
See related
Ensembl:ENSMUSG00000046027 AllianceGenome:MGI:2156765
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D7Ertd152e; 2310058G22Rik
Summary
Predicted to enable cholesterol binding activity and cholesterol transfer activity. Predicted to be involved in cholesterol import. Predicted to act upstream of or within intermembrane lipid transfer and sterol transport. Is expressed in embryo; liver; and metanephros. Orthologous to human STARD5 (StAR related lipid transfer domain containing 5). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in kidney adult (RPKM 30.6), liver adult (RPKM 26.0) and 28 other tissues See more
Orthologs
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Genomic context

See Stard5 in Genome Data Viewer
Location:
7 D3; 7 47.43 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (83281225..83291536)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (83632017..83642328)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene 10610 Neighboring gene STARR-seq mESC enhancer starr_19409 Neighboring gene transmembrane channel-like gene family 3 Neighboring gene predicted gene, 16638 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:90803780-90804044 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:90809590-90809791 Neighboring gene interleukin 16 Neighboring gene STARR-positive B cell enhancer ABC_E8840 Neighboring gene 3-phosphoglycerate dehydrogenase, pseudogene 1 Neighboring gene heterogeneous nuclear ribonucleoprotein K pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (1) 

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables cholesterol binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables cholesterol binding ISA
Inferred from Sequence Alignment
more info
PubMed 
enables cholesterol binding ISO
Inferred from Sequence Orthology
more info
 
enables cholesterol transfer activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables cholesterol transfer activity ISO
Inferred from Sequence Orthology
more info
 
enables lipid binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cholesterol import IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cholesterol import ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within lipid transport IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
stAR-related lipid transfer protein 5
Names
18B7-T7(GS)
START domain-containing protein 5
StAR-related lipid transfer (START) domain containing 5
StAR-related protein 1-4E
StAR-related protein p3-15E/p3-16E

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_023377.4NP_075866.2  stAR-related lipid transfer protein 5

    See identical proteins and their annotated locations for NP_075866.2

    Status: PROVISIONAL

    Source sequence(s)
    BC058226
    Consensus CDS
    CCDS21411.1
    UniProtKB/Swiss-Prot
    Q9CQY0, Q9EPQ6, Q9EPQ7
    Related
    ENSMUSP00000074872.8, ENSMUST00000075418.15
    Conserved Domains (1) summary
    cl14643
    Location:6211
    SRPBCC; START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    83281225..83291536
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)