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FUT11 fucosyltransferase 11 [ Homo sapiens (human) ]

Gene ID: 170384, updated on 11-Jun-2021

Summary

Official Symbol
FUT11provided by HGNC
Official Full Name
fucosyltransferase 11provided by HGNC
Primary source
HGNC:HGNC:19233
See related
Ensembl:ENSG00000196968 MIM:616932
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FUCTXI
Expression
Ubiquitous expression in placenta (RPKM 8.2), lung (RPKM 6.0) and 24 other tissues See more
Orthologs
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Genomic context

See FUT11 in Genome Data Viewer
Location:
10q22.2
Exon count:
4
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (73772276..73779104)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (75532034..75535977)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene glutamate dehydrogenase 1 pseudogene 3 Neighboring gene dual specificity phosphatase 8 pseudogene 5 Neighboring gene SEC24 homolog C, COPII coat complex component Neighboring gene uncharacterized LOC107984243 Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC33202, MGC119338, MGC119339

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables alpha-(1->3)-fucosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in fucosylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in Golgi cisterna membrane IEA
Inferred from Electronic Annotation
more info
 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
alpha-(1,3)-fucosyltransferase 11
Names
alpha (1,3) fucosyltransferase
fuc-TXI
fucT-XI
fucosyltransferase XI
galactoside 3-L-fucosyltransferase 11
NP_001271123.1
NP_775811.2
XP_006717719.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001284194.2NP_001271123.1  alpha-(1,3)-fucosyltransferase 11 isoform 2 precursor

    See identical proteins and their annotated locations for NP_001271123.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region, which results in a frameshift, compared to variant 1. It encodes isoform 2, which has a shorter and distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AC022400, BC036037, BC100994
    Consensus CDS
    CCDS60558.1
    UniProtKB/Swiss-Prot
    Q495W5
    Related
    ENSP00000378270.1, ENST00000394790.2
    Conserved Domains (2) summary
    pfam00852
    Location:216355
    Glyco_transf_10; Glycosyltransferase family 10 (fucosyltransferase) C-term
    pfam17039
    Location:77176
    Glyco_tran_10_N; Fucosyltransferase, N-terminal
  2. NM_173540.3NP_775811.2  alpha-(1,3)-fucosyltransferase 11 isoform 1 precursor

    See identical proteins and their annotated locations for NP_775811.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the shorter transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC022400, BC036037, BC100997
    Consensus CDS
    CCDS7333.1
    UniProtKB/Swiss-Prot
    Q495W5
    Related
    ENSP00000361932.3, ENST00000372841.8
    Conserved Domains (2) summary
    pfam00852
    Location:216355
    Glyco_transf_10; Glycosyltransferase family 10 (fucosyltransferase) C-term
    pfam17039
    Location:77176
    Glyco_tran_10_N; Fucosyltransferase, N-terminal

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

    Range
    73772276..73779104
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006717656.4XP_006717719.1  alpha-(1,3)-fucosyltransferase 11 isoform X1

    Conserved Domains (2) summary
    pfam00852
    Location:216355
    Glyco_transf_10; Glycosyltransferase family 10 (fucosyltransferase) C-term
    pfam17039
    Location:77176
    Glyco_tran_10_N; Fucosyltransferase, N-terminal

RNA

  1. XR_002956964.1 RNA Sequence

  2. XR_001747050.2 RNA Sequence

  3. XR_001747049.2 RNA Sequence

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