Format

Send to:

Choose Destination

FAM170B family with sequence similarity 170 member B [ Homo sapiens (human) ]

Gene ID: 170370, updated on 23-Nov-2021

Summary

Official Symbol
FAM170Bprovided by HGNC
Official Full Name
family with sequence similarity 170 member Bprovided by HGNC
Primary source
HGNC:HGNC:19736
See related
Ensembl:ENSG00000172538
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C10orf73
Expression
Restricted expression toward testis (RPKM 3.2) See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See FAM170B in Genome Data Viewer
Location:
10q11.23
Exon count:
2
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (49131154..49134021, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (50339199..50342066, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene microRNA 4294 Neighboring gene V-set and transmembrane domain containing 4 Neighboring gene FAM170B antisense RNA 1 Neighboring gene transmembrane protein 273 Neighboring gene C10orf71 antisense RNA 1 Neighboring gene chromosome 10 open reading frame 71

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Homology

Clone Names

  • AC084727.4

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in fertilization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of acrosome reaction ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in regulation of fertilization ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
is_active_in acrosomal vesicle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in acrosomal vesicle IDA
Inferred from Direct Assay
more info
PubMed 
located_in outer acrosomal membrane ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
protein FAM170B
Names
acrosome-related protein
putative protein FAM170B

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164484.2NP_001157956.1  protein FAM170B

    See identical proteins and their annotated locations for NP_001157956.1

    Status: VALIDATED

    Source sequence(s)
    AC084727
    Consensus CDS
    CCDS53536.1
    UniProtKB/Swiss-Prot
    A6NMN3
    Related
    ENSP00000308292.6, ENST00000311787.6

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

    Range
    49131154..49134021 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center