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Psmb9 proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) [ Mus musculus (house mouse) ]

Gene ID: 16912, updated on 23-May-2018
Official Symbol
Psmb9provided by MGI
Official Full Name
proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)provided by MGI
Primary source
MGI:MGI:1346526
See related
Ensembl:ENSMUSG00000096727 Vega:OTTMUSG00000036472
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Lmp2; Lmp-2
Expression
Broad expression in large intestine adult (RPKM 97.4), thymus adult (RPKM 90.4) and 16 other tissues See more
Orthologs
See Psmb9 in Genome Data Viewer
Location:
17 B1; 17 17.98 cM
Exon count:
7
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 17 NC_000083.6 (34182030..34187330, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (34319044..34324275, complement)

Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene histocompatibility 2, class II, locus Mb2 Neighboring gene histocompatibility 2, class II, locus Mb1 Neighboring gene transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) Neighboring gene proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
peptidase activity IEA
Inferred from Electronic Annotation
more info
 
proteasome binding ISO
Inferred from Sequence Orthology
more info
 
threonine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
antigen processing and presentation IDA
Inferred from Direct Assay
more info
PubMed 
antigen processing and presentation IMP
Inferred from Mutant Phenotype
more info
PubMed 
immune system process IEA
Inferred from Electronic Annotation
more info
 
proteasomal protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
proteasomal ubiquitin-independent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
proteolysis IEA
Inferred from Electronic Annotation
more info
 
proteolysis involved in cellular protein catabolic process IEA
Inferred from Electronic Annotation
more info
 
regulation of cysteine-type endopeptidase activity ISO
Inferred from Sequence Orthology
more info
 
response to bacterium IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
proteasome complex ISO
Inferred from Sequence Orthology
more info
 
proteasome core complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
proteasome core complex IDA
Inferred from Direct Assay
more info
PubMed 
spermatoproteasome complex IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
proteasome subunit beta type-9
Names
LMP-2d
large multifunctional protease 2
low molecular mass protein 2
macropain chain 7
multicatalytic endopeptidase complex chain 7
proteasome chain 7
proteasome subunit beta-1i
proteosome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
proteosome beta 9 subunit
really interesting new gene 12 protein
NP_038613.1
XP_006523793.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013585.2NP_038613.1  proteasome subunit beta type-9

    See identical proteins and their annotated locations for NP_038613.1

    Status: PROVISIONAL

    Source sequence(s)
    CR974422
    Consensus CDS
    CCDS28642.1
    UniProtKB/Swiss-Prot
    P28076
    UniProtKB/TrEMBL
    A0A0R4J256
    Related
    ENSMUSP00000133499.1, OTTMUSP00000051839, ENSMUST00000174576.2, OTTMUST00000093460
    Conserved Domains (2) summary
    COG0638
    Location:13219
    PRE1; 20S proteasome, alpha and beta subunits [Posttranslational modification, protein turnover, chaperones]
    cd03762
    Location:21207
    proteasome_beta_type_6; proteasome beta type-6 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000083.6 Reference GRCm38.p4 C57BL/6J

    Range
    34182030..34187330 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006523730.2XP_006523793.1  proteasome subunit beta type-9 isoform X1

    See identical proteins and their annotated locations for XP_006523793.1

    Conserved Domains (2) summary
    COG0638
    Location:2196
    PRE1; 20S proteasome, alpha and beta subunits [Posttranslational modification, protein turnover, chaperones]
    cd03762
    Location:1184
    proteasome_beta_type_6; proteasome beta type-6 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that ...

Reference GRCm38.p4 129X1/SvJ

Genomic

  1. NT_039662.3 Reference GRCm38.p4 129X1/SvJ

    Range
    431016..436247 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCm38.p4 NOD/MrkTac

Genomic

  1. NT_187027.1 Reference GRCm38.p4 NOD/MrkTac

    Range
    493874..499101 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCm38.p4 NOD/ShiLtJ

Genomic

  1. NT_187004.1 Reference GRCm38.p4 NOD/ShiLtJ

    Range
    494077..499304 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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