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BHLHA15 basic helix-loop-helix family member a15 [ Homo sapiens (human) ]

Gene ID: 168620, updated on 17-Jun-2019

Summary

Official Symbol
BHLHA15provided by HGNC
Official Full Name
basic helix-loop-helix family member a15provided by HGNC
Primary source
HGNC:HGNC:22265
See related
Ensembl:ENSG00000180535 MIM:608606
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MIST1; BHLHB8
Orthologs

Genomic context

See BHLHA15 in Genome Data Viewer
Location:
7q21.3
Exon count:
1
Annotation release Status Assembly Chr Location
109.20190607 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (98212254..98212959)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (97840759..97844769)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene RNA, 7SL, cytoplasmic 478, pseudogene Neighboring gene lemur tyrosine kinase 2 Neighboring gene tectonin beta-propeller repeat containing 1 Neighboring gene BAI1 associated protein 2 like 1 Neighboring gene brain protein I3

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

  • Maturity onset diabetes of the young, organism-specific biosystem (from KEGG)
    Maturity onset diabetes of the young, organism-specific biosystemAbout 2-5% of type II diabetic patients suffer from a monogenic disease with autosomal dominant inheritance. This monogenic form of type II diabetes is called maturity onset diabetes of the young (MO...
  • Maturity onset diabetes of the young, conserved biosystem (from KEGG)
    Maturity onset diabetes of the young, conserved biosystemAbout 2-5% of type II diabetic patients suffer from a monogenic disease with autosomal dominant inheritance. This monogenic form of type II diabetes is called maturity onset diabetes of the young (MO...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
Golgi organization IEA
Inferred from Electronic Annotation
more info
 
calcium-mediated signaling IEA
Inferred from Electronic Annotation
more info
 
cell maturation IEA
Inferred from Electronic Annotation
more info
 
cell-cell signaling IEA
Inferred from Electronic Annotation
more info
 
cellular response to glucose starvation ISS
Inferred from Sequence or Structural Similarity
more info
 
endoplasmic reticulum unfolded protein response ISS
Inferred from Sequence or Structural Similarity
more info
 
glucose homeostasis IEA
Inferred from Electronic Annotation
more info
 
intracellular distribution of mitochondria IEA
Inferred from Electronic Annotation
more info
 
mitochondrial calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
negative regulation of myotube differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
class A basic helix-loop-helix protein 15
Names
MIST-1
basic helix-loop-helix domain containing, class B, 8
class B basic helix-loop-helix protein 8
class II bHLH protein MIST1
muscle, intestine and stomach expression 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177455.3NP_803238.1  class A basic helix-loop-helix protein 15

    See identical proteins and their annotated locations for NP_803238.1

    Status: VALIDATED

    Source sequence(s)
    BC113396
    Consensus CDS
    CCDS5655.1
    UniProtKB/Swiss-Prot
    Q7RTS1
    Related
    ENSP00000326391.2, ENST00000314018.2
    Conserved Domains (1) summary
    smart00353
    Location:81127
    HLH; helix loop helix domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    98212254..98212959
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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