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BHLHA15 basic helix-loop-helix family member a15 [ Homo sapiens (human) ]

Gene ID: 168620, updated on 11-Jul-2021

Summary

Official Symbol
BHLHA15provided by HGNC
Official Full Name
basic helix-loop-helix family member a15provided by HGNC
Primary source
HGNC:HGNC:22265
See related
Ensembl:ENSG00000180535 MIM:608606
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MIST1; BHLHB8
Orthologs
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Genomic context

See BHLHA15 in Genome Data Viewer
Location:
7q21.3
Exon count:
2
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (98211439..98215457)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (97840751..97844769)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene RNA, 7SL, cytoplasmic 478, pseudogene Neighboring gene lemur tyrosine kinase 2 Neighboring gene tectonin beta-propeller repeat containing 1 Neighboring gene Sharpr-MPRA regulatory region 13100 Neighboring gene BAR/IMD domain containing adaptor protein 2 like 1 Neighboring gene brain protein I3

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in Golgi organization IEA
Inferred from Electronic Annotation
more info
 
involved_in calcium-mediated signaling IEA
Inferred from Electronic Annotation
more info
 
involved_in cell maturation IEA
Inferred from Electronic Annotation
more info
 
involved_in cell-cell signaling IEA
Inferred from Electronic Annotation
more info
 
involved_in cellular response to glucose starvation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in endoplasmic reticulum unfolded protein response ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in glucose homeostasis IEA
Inferred from Electronic Annotation
more info
 
involved_in intracellular distribution of mitochondria IEA
Inferred from Electronic Annotation
more info
 
involved_in mitochondrial calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of myotube differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in neuron differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in chromatin ISA
Inferred from Sequence Alignment
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
class A basic helix-loop-helix protein 15
Names
MIST-1
basic helix-loop-helix domain containing, class B, 8
class B basic helix-loop-helix protein 8
class II bHLH protein MIST1
muscle, intestine and stomach expression 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177455.4NP_803238.1  class A basic helix-loop-helix protein 15

    See identical proteins and their annotated locations for NP_803238.1

    Status: VALIDATED

    Source sequence(s)
    AC091654
    Consensus CDS
    CCDS5655.1
    UniProtKB/Swiss-Prot
    Q7RTS1
    Related
    ENSP00000476312.1, ENST00000609256.2
    Conserved Domains (1) summary
    smart00353
    Location:81127
    HLH; helix loop helix domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    98211439..98215457
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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