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Lgals7 lectin, galactose binding, soluble 7 [ Mus musculus (house mouse) ]

Gene ID: 16858, updated on 12-May-2024

Summary

Official Symbol
Lgals7provided by MGI
Official Full Name
lectin, galactose binding, soluble 7provided by MGI
Primary source
MGI:MGI:1316742
See related
Ensembl:ENSMUSG00000053522 AllianceGenome:MGI:1316742
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Pig1; Galectin-7
Summary
Predicted to enable carbohydrate binding activity and galactoside binding activity. Predicted to be involved in negative regulation of CD4-positive, alpha-beta T cell proliferation; negative regulation of interferon-gamma production; and positive regulation of gene expression. Predicted to act upstream of or within apoptotic process. Predicted to be located in cytoplasm and extracellular space. Predicted to be active in cytosol and nucleus. Is expressed in maxillary process and upper jaw. Orthologous to several human genes including LGALS7 (galectin 7). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in stomach adult (RPKM 383.9), lung adult (RPKM 28.9) and 1 other tissue See more
Orthologs
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Genomic context

See Lgals7 in Genome Data Viewer
Location:
7 B1; 7 16.94 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (28563258..28565711)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (28863796..28866285)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_18440 Neighboring gene enoyl coenzyme A hydratase 1, peroxisomal Neighboring gene lectin, galactose binding, soluble 4 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:29650992-29651179 Neighboring gene predicted gene 10648 Neighboring gene calpain 12 Neighboring gene predicted gene 44700

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Clone Names

  • MGC151215, MGC151217

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables carbohydrate binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within apoptotic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cornified envelope IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001403038.1NP_001389967.1  galectin-7

    Status: VALIDATED

    Source sequence(s)
    AC171210
    UniProtKB/TrEMBL
    D3Z141, Q9CRB1
    Related
    ENSMUSP00000123110.3, ENSMUST00000138272.9
  2. NM_008496.5NP_032522.2  galectin-7

    See identical proteins and their annotated locations for NP_032522.2

    Status: VALIDATED

    Source sequence(s)
    AC171210
    Consensus CDS
    CCDS21060.1
    UniProtKB/TrEMBL
    D3Z141, Q9CRB1, Q9D7K4
    Related
    ENSMUSP00000080179.5, ENSMUST00000081457.5
    Conserved Domains (1) summary
    pfam00337
    Location:5133
    Gal-bind_lectin; Galactoside-binding lectin

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    28563258..28565711
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)