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GIMAP7 GTPase, IMAP family member 7 [ Homo sapiens (human) ]

Gene ID: 168537, updated on 1-Jun-2020

Summary

Official Symbol
GIMAP7provided by HGNC
Official Full Name
GTPase, IMAP family member 7provided by HGNC
Primary source
HGNC:HGNC:22404
See related
Ensembl:ENSG00000179144 MIM:616961
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
IAN7; hIAN7
Summary
This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. [provided by RefSeq, Jul 2008]
Expression
Broad expression in lymph node (RPKM 74.8), spleen (RPKM 59.3) and 19 other tissues See more
Orthologs

Genomic context

See GIMAP7 in Genome Data Viewer
Location:
7q36.1
Exon count:
2
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (150514872..150521073)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (150211945..150218161)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 2A pseudogene 1 Neighboring gene STE20-related kinase adaptor beta pseudogene 1 Neighboring gene aldehyde dehydrogenase 7 family member A1 pseudogene 3 Neighboring gene endogenous retrovirus group K member 19 Env polyprotein-like

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • MGC27027

Gene Ontology Provided by GOA

Function Evidence Code Pubs
GTP binding IDA
Inferred from Direct Assay
more info
PubMed 
GTPase activity IDA
Inferred from Direct Assay
more info
PubMed 
identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein homodimerization activity IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
GTP metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
 
endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
intracellular membrane-bounded organelle IDA
Inferred from Direct Assay
more info
 
lipid droplet IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
GTPase IMAP family member 7
Names
IAN-7
immune associated nucleotide
immune-associated nucleotide-binding protein 7
immunity-associated nucleotide 7 protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153236.4NP_694968.1  GTPase IMAP family member 7

    See identical proteins and their annotated locations for NP_694968.1

    Status: REVIEWED

    Source sequence(s)
    AA854865, BC027613, BX440511
    Consensus CDS
    CCDS5903.1
    UniProtKB/Swiss-Prot
    Q8NHV1
    UniProtKB/TrEMBL
    A0A090N8P8
    Related
    ENSP00000315474.4, ENST00000313543.5
    Conserved Domains (1) summary
    cd01852
    Location:9211
    AIG1; AvrRpt2-Induced Gene 1 (AIG1)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    150514872..150521073
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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