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TXLNB taxilin beta [ Homo sapiens (human) ]

Gene ID: 167838, updated on 21-Dec-2019

Summary

Official Symbol
TXLNBprovided by HGNC
Official Full Name
taxilin betaprovided by HGNC
Primary source
HGNC:HGNC:21617
See related
Ensembl:ENSG00000164440 MIM:611438
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MDP77; LST001; C6orf198; dJ522B19.2
Expression
Biased expression in heart (RPKM 26.4), ovary (RPKM 5.2) and 4 other tissues See more
Orthologs

Genomic context

See TXLNB in Genome Data Viewer
Location:
6q24.1
Exon count:
18
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 6 NC_000006.12 (139159162..139324029, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (139561198..139645148, complement)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene ABRA C-terminal like Neighboring gene Sharpr-MPRA regulatory region 4168 Neighboring gene hdc homolog, cell cycle regulator Neighboring gene uncharacterized LOC102723690 Neighboring gene DnaJ heat shock protein family (Hsp40) member C7 pseudogene Neighboring gene Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Vif vif HIV-1 Vif downregulates the expression of taxilin beta (TXLNB) in Vif-expression T cells PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • DKFZp451A175

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
syntaxin binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
beta-taxilin
Names
muscle-derived protein 77

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153235.4NP_694967.3  beta-taxilin

    See identical proteins and their annotated locations for NP_694967.3

    Status: VALIDATED

    Source sequence(s)
    AB085905, AL158850
    Consensus CDS
    CCDS34545.1
    UniProtKB/Swiss-Prot
    Q8N3L3
    Related
    ENSP00000351206.3, ENST00000358430.8
    Conserved Domains (2) summary
    pfam09728
    Location:143450
    Taxilin; Myosin-like coiled-coil protein
    cl26386
    Location:519683
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p13 Primary Assembly

    Range
    139159162..139324029 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024446341.1XP_024302109.1  beta-taxilin isoform X1

    Conserved Domains (2) summary
    pfam09728
    Location:143450
    Taxilin; Myosin-like coiled-coil protein
    cl26386
    Location:519683
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
  2. XM_005266836.1XP_005266893.1  beta-taxilin isoform X1

    See identical proteins and their annotated locations for XP_005266893.1

    UniProtKB/Swiss-Prot
    Q8N3L3
    Conserved Domains (2) summary
    pfam09728
    Location:143450
    Taxilin; Myosin-like coiled-coil protein
    cl26386
    Location:519683
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
  3. XM_011535505.3XP_011533807.1  beta-taxilin isoform X1

    See identical proteins and their annotated locations for XP_011533807.1

    UniProtKB/Swiss-Prot
    Q8N3L3
    Conserved Domains (2) summary
    pfam09728
    Location:143450
    Taxilin; Myosin-like coiled-coil protein
    cl26386
    Location:519683
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
  4. XM_017010322.2XP_016865811.1  beta-taxilin isoform X1

    UniProtKB/Swiss-Prot
    Q8N3L3
    Conserved Domains (2) summary
    pfam09728
    Location:143450
    Taxilin; Myosin-like coiled-coil protein
    cl26386
    Location:519683
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
  5. XM_011535506.2XP_011533808.1  beta-taxilin isoform X2

    See identical proteins and their annotated locations for XP_011533808.1

    UniProtKB/TrEMBL
    H0UI60
    Conserved Domains (2) summary
    pfam09728
    Location:1303
    Taxilin; Myosin-like coiled-coil protein
    cl19219
    Location:129204
    DUF342; Protein of unknown function (DUF342)

RNA

  1. XR_942317.3 RNA Sequence

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