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CDC20B cell division cycle 20B [ Homo sapiens (human) ]

Gene ID: 166979, updated on 11-Jun-2021

Summary

Official Symbol
CDC20Bprovided by HGNC
Official Full Name
cell division cycle 20Bprovided by HGNC
Primary source
HGNC:HGNC:24222
See related
Ensembl:ENSG00000164287
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
G6VTS76519
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See CDC20B in Genome Data Viewer
Location:
5q11.2
Exon count:
13
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (55112971..55173177, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (54408799..54469005, complement)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene granzyme A pseudogene 1 Neighboring gene granzyme A Neighboring gene glutathione peroxidase 8 (putative) Neighboring gene microRNA 449a Neighboring gene microRNA 449b Neighboring gene microRNA 449c Neighboring gene multiciliate differentiation and DNA synthesis associated cell cycle protein Neighboring gene cyclin O

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ37927

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables anaphase-promoting complex binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables ubiquitin ligase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
part_of anaphase-promoting complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
cell division cycle protein 20 homolog B
Names
CDC20 cell division cycle 20 homolog B
CDC20-like protein
cell division cycle 20 homolog B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145734.2NP_001139206.2  cell division cycle protein 20 homolog B isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an exon in the 3' coding region but maintains the reading frame, compared to variant 3. This variant encodes isoform 2, which is shorter than isoform 3.
    Source sequence(s)
    AB086378, AC091977, AK095246, DB237622
    Consensus CDS
    CCDS47207.1
    UniProtKB/Swiss-Prot
    Q86Y33
    Related
    ENSP00000315720.6, ENST00000322374.10
    Conserved Domains (3) summary
    COG2319
    Location:183476
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:277313
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:236475
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  2. NM_001170402.1NP_001163873.1  cell division cycle protein 20 homolog B isoform 3

    See identical proteins and their annotated locations for NP_001163873.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (3).
    Source sequence(s)
    AC091977, AK095246, BC136572, DB237622
    Consensus CDS
    CCDS54852.1
    UniProtKB/Swiss-Prot
    Q86Y33
    Related
    ENSP00000370781.2, ENST00000381375.7
    Conserved Domains (3) summary
    COG2319
    Location:230518
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:276313
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:276517
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  3. NM_152623.2NP_689836.2  cell division cycle protein 20 homolog B isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) uses an alternate in-frame splice site in the 3' coding region, compared to variant 3. This results in a shorter protein (isoform 1), compared to isoform 3.
    Source sequence(s)
    AC091977, AI471861, AK095246, DB237622
    Consensus CDS
    CCDS3966.1
    UniProtKB/Swiss-Prot
    Q86Y33
    Related
    ENSP00000296733.1, ENST00000296733.5
    Conserved Domains (3) summary
    COG2319
    Location:230514
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:276313
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:276513
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    55112971..55173177 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011543218.2XP_011541520.1  cell division cycle protein 20 homolog B isoform X1

    Related
    ENSP00000423919.1, ENST00000507931.1
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