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Krt32 keratin 32 [ Mus musculus (house mouse) ]

Gene ID: 16670, updated on 30-Apr-2024

Summary

Official Symbol
Krt32provided by MGI
Official Full Name
keratin 32provided by MGI
Primary source
MGI:MGI:1309995
See related
Ensembl:ENSMUSG00000046095 AllianceGenome:MGI:1309995
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ha3; K32; Hka2; Krt1-2; Krtha2
Summary
Predicted to enable structural molecule activity. Predicted to be located in intermediate filament. Is expressed in esophagus; jaw bone; lung; skin; and urethra. Orthologous to human KRT32 (keratin 32). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in lung adult (RPKM 3.1), stomach adult (RPKM 1.0) and 2 other tissues See more
Orthologs
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Genomic context

See Krt32 in Genome Data Viewer
Location:
11 D; 11 63.4 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (99971674..99979095, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (100080848..100088269, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene keratin 34 Neighboring gene keratin 31 Neighboring gene predicted gene 11571 Neighboring gene STARR-seq mESC enhancer starr_30712 Neighboring gene keratin 35 Neighboring gene keratin 36

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (5) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC144672, MGC144673

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in epithelial cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intermediate filament organization IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in intermediate filament IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
keratin, type I cuticular Ha2
Names
hair keratin, type I Ha2
keratin complex 1, acidic, gene 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001159374.3NP_001152846.2  keratin, type I cuticular Ha2

    Status: VALIDATED

    Source sequence(s)
    AL662808
    Consensus CDS
    CCDS56805.1
    UniProtKB/Swiss-Prot
    Q148N4, Q62168
    UniProtKB/TrEMBL
    B1ATJ5
    Related
    ENSMUSP00000103042.2, ENSMUST00000107419.3
    Conserved Domains (3) summary
    pfam00038
    Location:100411
    Filament; Intermediate filament protein
    pfam05287
    Location:192
    PMG; PMG protein
    pfam16043
    Location:102256
    DUF4795; Domain of unknown function (DUF4795)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    99971674..99979095 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_010665.2: Suppressed sequence

    Description
    NM_010665.2: This RefSeq was temporarily suppressed because the CDS was partial.