Klra12 killer cell lectin-like receptor subfamily A, member 12 [Mus musculus (house mouse)] - Gene

Summary

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Official Symbol: Klra12provided by MGI
Official Full Name: killer cell lectin-like receptor subfamily A, member 12provided by MGI
Primary source: MGI:MGI:1321091
See related: AllianceGenome:MGI:1321091
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Ly49L; Ly49l1; Ly49l2; Ly49l3; Ly49l4; Ly49p/d
Summary: Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
Annotation information: not in current annotation release
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Genomic context

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See Klra12 in Genome Data Viewer

Location:: 6 F3; 6

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The distinct conformations (backfolded and extended) define the structural basis for cis-trans binding by Ly49 receptors and explain the divergent functional consequences of cis versus trans interactions.
Title: Distinct conformations of Ly49 natural killer cell receptors mediate MHC class I recognition in trans and cis.

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General protein information

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Preferred Names: killer cell lectin-like receptor subfamily A, member 12

Names: novel killer cell lectin-like receptor, subfamily A protein

NP_034776.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_010646.1 → NP_034776.1 killer cell lectin-like receptor subfamily A, member 12

See identical proteins and their annotated locations for NP_034776.1

Status: PROVISIONAL

Source sequence(s)

AF307948

UniProtKB/TrEMBL

Q9JIP9, Q9JIQ1

Conserved Domains (2) summary

cd03593
Location:143 → 258

CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)

pfam08391
Location:38 → 156

Ly49; Ly49-like protein, N-terminal region