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DQX1 DEAQ-box RNA dependent ATPase 1 [ Homo sapiens (human) ]

Gene ID: 165545, updated on 1-Jun-2020

Summary

Official Symbol
DQX1provided by HGNC
Official Full Name
DEAQ-box RNA dependent ATPase 1provided by HGNC
Primary source
HGNC:HGNC:20410
See related
Ensembl:ENSG00000144045
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Biased expression in duodenum (RPKM 13.5), small intestine (RPKM 12.8) and 6 other tissues See more
Orthologs

Genomic context

See DQX1 in Genome Data Viewer
Location:
2p13.1
Exon count:
12
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 2 NC_000002.12 (74518131..74526231, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (74745258..74753408, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene LBX2 antisense RNA 1 Neighboring gene polycomb group ring finger 1 Neighboring gene T cell leukemia homeobox 2 Neighboring gene AUP1 lipid droplet regulating VLDL assembly factor Neighboring gene HtrA serine peptidase 2 Neighboring gene lysyl oxidase like 3 Neighboring gene docking protein 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ23757

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
DNA helicase activity IEA
Inferred from Electronic Annotation
more info
 
RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
DNA duplex unwinding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
intracellular IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
spliceosomal complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
ATP-dependent RNA helicase DQX1
Names
DEAQ RNA-dependent ATPase DQX1
DEAQ box polypeptide 1 (RNA-dependent ATPase)
NP_598376.2
XP_011530947.1
XP_016859009.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_133637.3NP_598376.2  ATP-dependent RNA helicase DQX1

    See identical proteins and their annotated locations for NP_598376.2

    Status: VALIDATED

    Source sequence(s)
    AA515987, BC033238, BC075018, BM987933, DA852016
    Consensus CDS
    CCDS1949.2
    UniProtKB/Swiss-Prot
    Q8TE96
    Related
    ENSP00000384621.3, ENST00000404568.4
    Conserved Domains (5) summary
    smart00487
    Location:41231
    DEXDc; DEAD-like helicases superfamily
    smart00847
    Location:465530
    HA2; Helicase associated domain (HA2) Add an annotation
    cd00046
    Location:65204
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cl22853
    Location:889
    Motor_domain; Myosin and Kinesin motor domain
    pfam07717
    Location:565674
    OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    74518131..74526231 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017003520.1XP_016859009.1  ATP-dependent RNA helicase DQX1 isoform X2

  2. XM_011532645.1XP_011530947.1  ATP-dependent RNA helicase DQX1 isoform X1

    Conserved Domains (2) summary
    smart00847
    Location:223288
    HA2; Helicase associated domain (HA2) Add an annotation
    pfam07717
    Location:323432
    OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold
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