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Kcns2 K+ voltage-gated channel, subfamily S, 2 [ Mus musculus (house mouse) ]

Gene ID: 16539, updated on 12-Aug-2019

Summary

Official Symbol
Kcns2provided by MGI
Official Full Name
K+ voltage-gated channel, subfamily S, 2provided by MGI
Primary source
MGI:MGI:1197011
See related
Ensembl:ENSMUSG00000050963
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Kv9.2; E130006J24Rik
Expression
Biased expression in cortex adult (RPKM 2.7), frontal lobe adult (RPKM 2.6) and 5 other tissues See more
Orthologs

Genomic context

See Kcns2 in Genome Data Viewer
Location:
15; 15 B3.1
Exon count:
3
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (34837355..34843407)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (34767136..34772092)

Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 22208 Neighboring gene NIPA-like domain containing 2 Neighboring gene RIKEN cDNA 4930413F20 gene Neighboring gene predicted gene, 32970 Neighboring gene serine/threonine kinase 3 Neighboring gene predicted gene, 52204 Neighboring gene predicted gene, 33497 Neighboring gene predicted gene, 52178

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (1) 

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ion channel activity IEA
Inferred from Electronic Annotation
more info
 
potassium channel activity IEA
Inferred from Electronic Annotation
more info
 
voltage-gated ion channel activity IEA
Inferred from Electronic Annotation
more info
 
voltage-gated potassium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
ion transport IEA
Inferred from Electronic Annotation
more info
 
potassium ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
potassium ion transport IDA
Inferred from Direct Assay
more info
PubMed 
protein homooligomerization IEA
Inferred from Electronic Annotation
more info
 
regulation of delayed rectifier potassium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of delayed rectifier potassium channel activity IDA
Inferred from Direct Assay
more info
PubMed 
regulation of ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
voltage-gated potassium channel complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
colocalizes_with voltage-gated potassium channel complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
potassium voltage-gated channel subfamily S member 2
Names
delayed-rectifier K(+) channel alpha subunit 2
voltage-gated potassium channel subunit Kv9.2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001271704.1NP_001258633.1  potassium voltage-gated channel subfamily S member 2

    See identical proteins and their annotated locations for NP_001258633.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AK039387, AK050926, BC059833, BE954026
    Consensus CDS
    CCDS27421.1
    UniProtKB/Swiss-Prot
    O35174
    Related
    ENSMUSP00000153984.1, ENSMUST00000228725.1
    Conserved Domains (2) summary
    pfam00520
    Location:186421
    Ion_trans; Ion transport protein
    pfam02214
    Location:19118
    BTB_2; BTB/POZ domain
  2. NM_181317.4NP_851834.1  potassium voltage-gated channel subfamily S member 2

    See identical proteins and their annotated locations for NP_851834.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AK050926, AK173110, BE954026
    Consensus CDS
    CCDS27421.1
    UniProtKB/Swiss-Prot
    O35174
    UniProtKB/TrEMBL
    Q69ZQ8
    Related
    ENSMUSP00000072645.3, ENSMUST00000072868.4
    Conserved Domains (2) summary
    pfam00520
    Location:186421
    Ion_trans; Ion transport protein
    pfam02214
    Location:19118
    BTB_2; BTB/POZ domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000081.6 Reference GRCm38.p6 C57BL/6J

    Range
    34837355..34843407
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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