U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

OXER1 oxoeicosanoid receptor 1 [ Homo sapiens (human) ]

Gene ID: 165140, updated on 27-Nov-2024

Summary

Official Symbol
OXER1provided by HGNC
Official Full Name
oxoeicosanoid receptor 1provided by HGNC
Primary source
HGNC:HGNC:24884
See related
Ensembl:ENSG00000162881 MIM:620064; AllianceGenome:HGNC:24884
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GPCR; GPR170; TG1019
Summary
Enables G protein-coupled receptor activity and icosanoid binding activity. Involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See OXER1 in Genome Data Viewer
Location:
2p21
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (42762499..42764135, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (42767768..42769404, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (42989639..42991275, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene metastasis associated 1 family member 3 Neighboring gene uncharacterized LOC105374555 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:42833249-42834000 Neighboring gene MPRA-validated peak3682 silencer Neighboring gene NANOG hESC enhancer GRCh37_chr2:42881137-42881638 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15651 Neighboring gene Sharpr-MPRA regulatory region 10188 Neighboring gene RNA, U6 small nuclear 137, pseudogene Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:42983755-42984326 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:42983184-42983754 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:42994558-42995463 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11411 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11412 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11413 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15652 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15653 Neighboring gene 3-hydroxyanthranilate 3,4-dioxygenase Neighboring gene FTO pseudogene 1

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

EBI GWAS Catalog

Description
Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations.
EBI GWAS Catalog

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
oxoeicosanoid receptor 1
Names
5-oxo-ETE G-protein coupled receptor
5-oxo-ETE acid G-protein-coupled receptor 1
G-protein coupled receptor 170
G-protein coupled receptor R527
G-protein coupled receptor TG1019
OXE receptor
oxoeicosanoid (OXE) receptor 1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_148962.5NP_683765.2  oxoeicosanoid receptor 1

    Status: VALIDATED

    Source sequence(s)
    AC098824
    Consensus CDS
    CCDS1810.2
    UniProtKB/Swiss-Prot
    Q86WP7, Q8NGW4, Q8TDS5
    Related
    ENSP00000367930.3, ENST00000378661.4
    Conserved Domains (1) summary
    cd15200
    Location:54327
    7tmA_OXER1; oxoeicosanoid receptor 1, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    42762499..42764135 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    42767768..42769404 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)