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F11r F11 receptor [ Mus musculus (house mouse) ]

Gene ID: 16456, updated on 28-Nov-2021

Summary

Official Symbol
F11rprovided by MGI
Official Full Name
F11 receptorprovided by MGI
Primary source
MGI:MGI:1321398
See related
Ensembl:ENSMUSG00000038235
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
JAM; Jcam; JAM-1; JAM-A; Jcam1; Ly106; ESTM33; AA638916; 9130004G24
Expression
Broad expression in large intestine adult (RPKM 80.5), lung adult (RPKM 57.6) and 21 other tissues See more
Orthologs
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Genomic context

See F11r in Genome Data Viewer
Location:
1 H3; 1 79.43 cM
Exon count:
10
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (171265129..171292161)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (171437561..171464593)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (173367692..173394724)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 Neighboring gene predicted gene, 26641 Neighboring gene predicted gene, 24871 Neighboring gene Aly/REF export factor 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables PDZ domain binding ISO
Inferred from Sequence Orthology
more info
 
enables integrin binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in actomyosin structure organization ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within cell adhesion IDA
Inferred from Direct Assay
more info
PubMed 
involved_in cell-cell adhesion ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to mechanical stimulus ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within epithelial cell differentiation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in establishment of endothelial intestinal barrier IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in establishment of endothelial intestinal barrier ISO
Inferred from Sequence Orthology
more info
 
involved_in intestinal absorption IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in intestinal absorption IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in intestinal absorption ISO
Inferred from Sequence Orthology
more info
 
involved_in leukocyte cell-cell adhesion ISO
Inferred from Sequence Orthology
more info
 
involved_in memory T cell extravasation ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of GTPase activity ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of stress fiber assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of GTPase activity ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of Rho protein signal transduction ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of blood pressure ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of establishment of endothelial barrier ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of platelet aggregation ISO
Inferred from Sequence Orthology
more info
 
involved_in protein localization to bicellular tight junction ISO
Inferred from Sequence Orthology
more info
 
involved_in protein localization to plasma membrane ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of actin cytoskeleton organization ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of actin cytoskeleton reorganization ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of bicellular tight junction assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of cell shape ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of cytokine production IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of cytoskeleton organization ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of membrane permeability IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of membrane permeability IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of membrane permeability ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in bicellular tight junction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in bicellular tight junction IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in bicellular tight junction ISO
Inferred from Sequence Orthology
more info
 
located_in cell junction IEA
Inferred from Electronic Annotation
more info
 
located_in cell-cell junction ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasmic vesicle ISO
Inferred from Sequence Orthology
more info
 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
 
located_in slit diaphragm ISO
Inferred from Sequence Orthology
more info
 
located_in tight junction ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
junctional adhesion molecule A
Names
BV11 antigen
F11 receptor/F11R
junction cell adhesion molecule A
junction cell adhesion molecule1
junctional adhesion molecule 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_172647.2NP_766235.1  junctional adhesion molecule A precursor

    See identical proteins and their annotated locations for NP_766235.1

    Status: VALIDATED

    Source sequence(s)
    AK033574, CJ317566
    Consensus CDS
    CCDS15496.1
    UniProtKB/Swiss-Prot
    O88792
    Related
    ENSMUSP00000041907.5, ENSMUST00000043839.5
    Conserved Domains (3) summary
    cd00096
    Location:148224
    Ig; Immunoglobulin domain
    smart00410
    Location:34127
    IG_like; Immunoglobulin like
    pfam07686
    Location:32128
    V-set; Immunoglobulin V-set domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    171265129..171292161
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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