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PAQR7 progestin and adipoQ receptor family member 7 [ Homo sapiens (human) ]

Gene ID: 164091, updated on 6-Jul-2025
Official Symbol
PAQR7provided by HGNC
Official Full Name
progestin and adipoQ receptor family member 7provided by HGNC
Primary source
HGNC:HGNC:23146
See related
Ensembl:ENSG00000182749 MIM:607779; AllianceGenome:HGNC:23146
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
mSR; MPRA; PGLP
Summary
Predicted to enable nuclear steroid receptor activity and steroid binding activity. Predicted to be involved in response to steroid hormone. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
Expression
Broad expression in kidney (RPKM 22.0), testis (RPKM 21.9) and 22 other tissues See more
Orthologs
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See PAQR7 in Genome Data Viewer
Location:
1p36.11
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (25861484..25875708, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (25698915..25713139, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (26187975..26202199, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 466 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 463 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 467 Neighboring gene uncharacterized LOC646471 Neighboring gene mitochondrial fission regulator 1 like Neighboring gene aurora kinase A and ninein interacting protein Neighboring gene hESC enhancers GRCh37_chr1:26185603-26186228 and GRCh37_chr1:26186229-26186854 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:26189139-26189908 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:26196207-26196708 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 469 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 470 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:26201379-26201878 Neighboring gene stathmin 1 Neighboring gene small nuclear ribonucleoprotein polypeptide F pseudogene 2 Neighboring gene ribosomal protein L39 pseudogene 7

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
Products Interactant Other Gene Complex Source Pubs Description

Markers

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables lipid binding IEA
Inferred from Electronic Annotation
more info
 
enables nuclear steroid receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables steroid binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables steroid binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 
involved_in nuclear receptor-mediated steroid hormone signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in oogenesis IEA
Inferred from Electronic Annotation
more info
 
involved_in response to steroid hormone IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
membrane progestin receptor alpha
Names
2310021M12Rik
mPR alpha
membrane progesterone P4 receptor alpha
membrane progesterone receptor alpha
progesterone and adipoQ receptor family member 7
progestin and adipoQ receptor family member VII

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178422.6NP_848509.1  membrane progestin receptor alpha

    See identical proteins and their annotated locations for NP_848509.1

    Status: VALIDATED

    Source sequence(s)
    AL033528
    Consensus CDS
    CCDS267.1
    UniProtKB/Swiss-Prot
    A2A2D3, Q5XKF9, Q86VE4, Q86WK9
    Related
    ENSP00000502514.1, ENST00000675840.1
    Conserved Domains (1) summary
    pfam03006
    Location:66290
    HlyIII; Haemolysin-III related

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    25861484..25875708 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005245746.4XP_005245803.1  membrane progestin receptor alpha isoform X1

    See identical proteins and their annotated locations for XP_005245803.1

    UniProtKB/Swiss-Prot
    A2A2D3, Q5XKF9, Q86VE4, Q86WK9
    Conserved Domains (1) summary
    pfam03006
    Location:66290
    HlyIII; Haemolysin-III related
  2. XM_011540862.3XP_011539164.1  membrane progestin receptor alpha isoform X1

    See identical proteins and their annotated locations for XP_011539164.1

    UniProtKB/Swiss-Prot
    A2A2D3, Q5XKF9, Q86VE4, Q86WK9
    Conserved Domains (1) summary
    pfam03006
    Location:66290
    HlyIII; Haemolysin-III related
  3. XM_047447964.1XP_047303920.1  membrane progestin receptor alpha isoform X1

    UniProtKB/Swiss-Prot
    A2A2D3, Q5XKF9, Q86VE4, Q86WK9

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    25698915..25713139 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054334782.1XP_054190757.1  membrane progestin receptor alpha isoform X1

    UniProtKB/Swiss-Prot
    A2A2D3, Q5XKF9, Q86VE4, Q86WK9
  2. XM_054334783.1XP_054190758.1  membrane progestin receptor alpha isoform X1

    UniProtKB/Swiss-Prot
    A2A2D3, Q5XKF9, Q86VE4, Q86WK9