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ZNF780B zinc finger protein 780B [ Homo sapiens (human) ]

Gene ID: 163131, updated on 13-Mar-2020

Summary

Official Symbol
ZNF780Bprovided by HGNC
Official Full Name
zinc finger protein 780Bprovided by HGNC
Primary source
HGNC:HGNC:33109
See related
Ensembl:ENSG00000128000
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZNF779
Expression
Ubiquitous expression in thyroid (RPKM 2.6), ovary (RPKM 2.0) and 24 other tissues See more
Orthologs

Genomic context

See ZNF780B in Genome Data Viewer
Location:
19q13.2
Exon count:
8
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (40028260..40064448, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (40534167..40562125, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 7932 Neighboring gene zinc finger protein 546 Neighboring gene PAT1 homolog 1, processing body mRNA decay factor pseudogene Neighboring gene zinc finger protein 780A Neighboring gene vomeronasal 1 receptor 96 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
zinc finger protein 780B
Names
zinc finger protein 779

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005851.3NP_001005851.1  zinc finger protein 780B

    See identical proteins and their annotated locations for NP_001005851.1

    Status: VALIDATED

    Source sequence(s)
    AC005614, AC007842, BC136960, CB053507
    Consensus CDS
    CCDS46077.1
    UniProtKB/Swiss-Prot
    Q9Y6R6
    UniProtKB/TrEMBL
    A0A024R0P7
    Related
    ENSP00000391641.1, ENST00000434248.6
    Conserved Domains (5) summary
    smart00349
    Location:666
    KRAB; krueppel associated box
    COG5048
    Location:191632
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:615635
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:645
    KRAB; KRAB box
    pfam13465
    Location:376400
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    40028260..40064448 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005258591.5XP_005258648.1  zinc finger protein 780B isoform X1

    See identical proteins and their annotated locations for XP_005258648.1

    Conserved Domains (5) summary
    smart00349
    Location:667
    KRAB; krueppel associated box
    COG5048
    Location:192633
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:336356
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:645
    KRAB; KRAB box
    pfam13465
    Location:377401
    zf-H2C2_2; Zinc-finger double domain
  2. XM_017026425.2XP_016881914.1  zinc finger protein 780B isoform X2

    UniProtKB/Swiss-Prot
    Q9Y6R6
    UniProtKB/TrEMBL
    A0A024R0P7
    Conserved Domains (5) summary
    smart00349
    Location:666
    KRAB; krueppel associated box
    COG5048
    Location:191632
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:615635
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:645
    KRAB; KRAB box
    pfam13465
    Location:376400
    zf-H2C2_2; Zinc-finger double domain
  3. XM_006723072.4XP_006723135.1  zinc finger protein 780B isoform X1

    See identical proteins and their annotated locations for XP_006723135.1

    Conserved Domains (5) summary
    smart00349
    Location:667
    KRAB; krueppel associated box
    COG5048
    Location:192633
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:336356
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:645
    KRAB; KRAB box
    pfam13465
    Location:377401
    zf-H2C2_2; Zinc-finger double domain
  4. XM_017026426.1XP_016881915.1  zinc finger protein 780B isoform X2

    UniProtKB/Swiss-Prot
    Q9Y6R6
    UniProtKB/TrEMBL
    A0A024R0P7
    Conserved Domains (5) summary
    smart00349
    Location:666
    KRAB; krueppel associated box
    COG5048
    Location:191632
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:615635
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:645
    KRAB; KRAB box
    pfam13465
    Location:376400
    zf-H2C2_2; Zinc-finger double domain
  5. XM_024451402.1XP_024307170.1  zinc finger protein 780B isoform X3

    Related
    ENSP00000221355.6, ENST00000221355.10
    Conserved Domains (2) summary
    COG5048
    Location:43484
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:467487
    ZF_C2H2; C2H2 Zn finger [structural motif]
  6. XM_024451403.1XP_024307171.1  zinc finger protein 780B isoform X3

    Conserved Domains (2) summary
    COG5048
    Location:43484
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:467487
    ZF_C2H2; C2H2 Zn finger [structural motif]
  7. XM_005258592.3XP_005258649.1  zinc finger protein 780B isoform X1

    See identical proteins and their annotated locations for XP_005258649.1

    Conserved Domains (5) summary
    smart00349
    Location:667
    KRAB; krueppel associated box
    COG5048
    Location:192633
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:336356
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:645
    KRAB; KRAB box
    pfam13465
    Location:377401
    zf-H2C2_2; Zinc-finger double domain
  8. XM_005258590.4XP_005258647.1  zinc finger protein 780B isoform X1

    See identical proteins and their annotated locations for XP_005258647.1

    Conserved Domains (5) summary
    smart00349
    Location:667
    KRAB; krueppel associated box
    COG5048
    Location:192633
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:336356
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:645
    KRAB; KRAB box
    pfam13465
    Location:377401
    zf-H2C2_2; Zinc-finger double domain
  9. XM_017026427.1XP_016881916.1  zinc finger protein 780B isoform X2

    UniProtKB/Swiss-Prot
    Q9Y6R6
    UniProtKB/TrEMBL
    A0A024R0P7
    Conserved Domains (5) summary
    smart00349
    Location:666
    KRAB; krueppel associated box
    COG5048
    Location:191632
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:615635
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:645
    KRAB; KRAB box
    pfam13465
    Location:376400
    zf-H2C2_2; Zinc-finger double domain
  10. XM_005258595.3XP_005258652.1  zinc finger protein 780B isoform X1

    See identical proteins and their annotated locations for XP_005258652.1

    Conserved Domains (5) summary
    smart00349
    Location:667
    KRAB; krueppel associated box
    COG5048
    Location:192633
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:336356
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:645
    KRAB; KRAB box
    pfam13465
    Location:377401
    zf-H2C2_2; Zinc-finger double domain
  11. XM_005258593.2XP_005258650.1  zinc finger protein 780B isoform X2

    See identical proteins and their annotated locations for XP_005258650.1

    UniProtKB/Swiss-Prot
    Q9Y6R6
    UniProtKB/TrEMBL
    A0A024R0P7
    Conserved Domains (5) summary
    smart00349
    Location:666
    KRAB; krueppel associated box
    COG5048
    Location:191632
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:615635
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:645
    KRAB; KRAB box
    pfam13465
    Location:376400
    zf-H2C2_2; Zinc-finger double domain
  12. XM_024451401.1XP_024307169.1  zinc finger protein 780B isoform X3

    Conserved Domains (2) summary
    COG5048
    Location:43484
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:467487
    ZF_C2H2; C2H2 Zn finger [structural motif]
  13. XM_011526593.2XP_011524895.1  zinc finger protein 780B isoform X1

    See identical proteins and their annotated locations for XP_011524895.1

    Conserved Domains (5) summary
    smart00349
    Location:667
    KRAB; krueppel associated box
    COG5048
    Location:192633
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:336356
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:645
    KRAB; KRAB box
    pfam13465
    Location:377401
    zf-H2C2_2; Zinc-finger double domain

Reference GRCh38.p13 PATCHES

Genomic

  1. NW_009646206.1 Reference GRCh38.p13 PATCHES

    Range
    303403..331374 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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