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ZNF791 zinc finger protein 791 [ Homo sapiens (human) ]

Gene ID: 163049, updated on 27-Nov-2022

Summary

Official Symbol
ZNF791provided by HGNC
Official Full Name
zinc finger protein 791provided by HGNC
Primary source
HGNC:HGNC:26895
See related
Ensembl:ENSG00000173875 AllianceGenome:HGNC:26895
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in thyroid (RPKM 9.3), ovary (RPKM 5.2) and 25 other tissues See more
Orthologs
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Genomic context

See ZNF791 in Genome Data Viewer
Location:
19p13.13
Exon count:
4
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (12610920..12633834)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (12735260..12758349)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (12721734..12744648)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene phosphoglycerate kinase 1, pseudogene 2 Neighboring gene zinc finger protein 490 Neighboring gene vomeronasal 2 receptor 16 pseudogene Neighboring gene uncharacterized LOC105372279 Neighboring gene ribosomal protein L10 pseudogene 16 Neighboring gene mannosidase alpha class 2B member 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

HIV-1 interactions

Replication interactions

Interaction Pubs
Knockdown of zinc finger protein 791 (ZNF791) by siRNA inhibits HIV-1 replication in HeLa-derived TZM-bl cells PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ90396, MGC126179, MGC126180

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153358.3NP_699189.2  zinc finger protein 791

    See identical proteins and their annotated locations for NP_699189.2

    Status: VALIDATED

    Source sequence(s)
    AC010422, AK074877, AK307775, BC106937, BP319293, DC329382
    Consensus CDS
    CCDS12273.1
    UniProtKB/Swiss-Prot
    Q3KP31, Q8NC99
    Related
    ENSP00000342974.4, ENST00000343325.9
    Conserved Domains (3) summary
    COG5048
    Location:98573
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:442462
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:344
    KRAB; KRAB box

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    12610920..12633834
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    12735260..12758349
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)