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ZNF320 zinc finger protein 320 [ Homo sapiens (human) ]

Gene ID: 162967, updated on 8-Dec-2022

Summary

Official Symbol
ZNF320provided by HGNC
Official Full Name
zinc finger protein 320provided by HGNC
Primary source
HGNC:HGNC:13842
See related
Ensembl:ENSG00000182986 MIM:606427; AllianceGenome:HGNC:13842
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZFPL
Summary
ZNF320 encodes a Kruppel-like zinc finger protein. Members of this protein family are involved in activation or repression of transcription.[supplied by OMIM, Jul 2002]
Expression
Ubiquitous expression in urinary bladder (RPKM 3.5), thyroid (RPKM 3.3) and 25 other tissues See more
Orthologs
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Try the new Transcript table

Genomic context

See ZNF320 in Genome Data Viewer
Location:
19q13.41
Exon count:
13
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (52859491..52904320, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (55943802..55982216, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (53362744..53400947, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 600 Neighboring gene zinc finger protein 28 Neighboring gene PABPN1 pseudogene 2 Neighboring gene zinc finger protein 468 Neighboring gene zinc finger protein 888 Neighboring gene ZNF816-ZNF321P readthrough Neighboring gene ZNF888 antisense RNA 1 Neighboring gene zinc finger protein 321, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • DKFZp686G16228

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 

General protein information

Preferred Names
zinc finger protein 320
Names
zinc finger gene 320
zinc finger protein like

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001351773.2NP_001338702.1  zinc finger protein 320 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1-5 encode the same protein (isoform 1).
    Source sequence(s)
    AC010487, AI344388, AK096348, BC131555, DA025391, DA742339
    Consensus CDS
    CCDS33095.1
    UniProtKB/Swiss-Prot
    Q8NDR6
    Related
    ENSP00000375660.2, ENST00000391781.6
    Conserved Domains (4) summary
    COG5048
    Location:147483
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:25216
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:303323
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:748
    KRAB; KRAB box
  2. NM_001351774.2NP_001338703.1  zinc finger protein 320 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1-5 encode the same protein (isoform 1).
    Source sequence(s)
    AC010487, AI344388, AK096348, BC105738, BC131555, DA742339, DA852671
    Consensus CDS
    CCDS33095.1
    UniProtKB/Swiss-Prot
    Q8NDR6
    Related
    ENSP00000506814.1, ENST00000682928.1
    Conserved Domains (4) summary
    COG5048
    Location:147483
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:25216
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:303323
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:748
    KRAB; KRAB box
  3. NM_001351775.2NP_001338704.1  zinc finger protein 320 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1-5 encode the same protein (isoform 1).
    Source sequence(s)
    AC010487, AI344388, AK096348, BC105738, BC131555, DA742339, DA852671
    Consensus CDS
    CCDS33095.1
    UniProtKB/Swiss-Prot
    Q8NDR6
    Conserved Domains (4) summary
    COG5048
    Location:147483
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:25216
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:303323
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:748
    KRAB; KRAB box
  4. NM_001351776.2NP_001338705.1  zinc finger protein 320 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. Variants 1-5 encode the same protein (isoform 1).
    Source sequence(s)
    AC010487, AI344388, AK096348, BC131555, DA742339, DA852671
    Consensus CDS
    CCDS33095.1
    UniProtKB/Swiss-Prot
    Q8NDR6
    Conserved Domains (4) summary
    COG5048
    Location:147483
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:25216
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:303323
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:748
    KRAB; KRAB box
  5. NM_001351777.2NP_001338706.1  zinc finger protein 320 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) contains two alternate exons in the 3' coding region, including an alternate terminal exon, compared to variant 1. The encoded isoform (2) is significantly shorter, and contains a distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AC008813, AC010487, CA425481, DA025391, DA415801, DA742339, DC418794
    Consensus CDS
    CCDS92678.1
    UniProtKB/TrEMBL
    A0A669KBJ2
    Conserved Domains (1) summary
    pfam01352
    Location:748
    KRAB; KRAB box
  6. NM_001387570.1NP_001374499.1  zinc finger protein 320 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC008813, AC010487
    Consensus CDS
    CCDS92678.1
    UniProtKB/TrEMBL
    A0A669KBJ2
    Related
    ENSP00000501288.1, ENST00000594408.3
    Conserved Domains (1) summary
    pfam01352
    Location:748
    KRAB; KRAB box
  7. NM_001387571.1NP_001374500.1  zinc finger protein 320 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC008813, AC010487
    Consensus CDS
    CCDS92678.1
    UniProtKB/TrEMBL
    A0A669KBJ2
    Related
    ENSP00000500974.1, ENST00000673631.1
    Conserved Domains (1) summary
    pfam01352
    Location:748
    KRAB; KRAB box
  8. NM_001387572.1NP_001374501.1  zinc finger protein 320 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC010487
    Consensus CDS
    CCDS33095.1
    UniProtKB/Swiss-Prot
    Q8NDR6
    Related
    ENSP00000473091.1, ENST00000595635.5
    Conserved Domains (4) summary
    COG5048
    Location:147483
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:25216
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:303323
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:748
    KRAB; KRAB box
  9. NM_001387573.1NP_001374502.1  zinc finger protein 320 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC010487
    Consensus CDS
    CCDS33095.1
    UniProtKB/Swiss-Prot
    Q8NDR6
    Conserved Domains (4) summary
    COG5048
    Location:147483
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:25216
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:303323
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:748
    KRAB; KRAB box
  10. NM_001387574.1NP_001374503.1  zinc finger protein 320 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC010487
    Consensus CDS
    CCDS33095.1
    UniProtKB/Swiss-Prot
    Q8NDR6
    Conserved Domains (4) summary
    COG5048
    Location:147483
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:25216
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:303323
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:748
    KRAB; KRAB box
  11. NM_001387575.1NP_001374504.1  zinc finger protein 320 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC010487
    Consensus CDS
    CCDS33095.1
    UniProtKB/Swiss-Prot
    Q8NDR6
    Conserved Domains (4) summary
    COG5048
    Location:147483
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:25216
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:303323
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:748
    KRAB; KRAB box
  12. NM_001387576.1NP_001374505.1  zinc finger protein 320 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC010487
    Consensus CDS
    CCDS33095.1
    UniProtKB/Swiss-Prot
    Q8NDR6
    Conserved Domains (4) summary
    COG5048
    Location:147483
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:25216
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:303323
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:748
    KRAB; KRAB box
  13. NM_001387577.1NP_001374506.1  zinc finger protein 320 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC010487
    Consensus CDS
    CCDS33095.1
    UniProtKB/Swiss-Prot
    Q8NDR6
    Conserved Domains (4) summary
    COG5048
    Location:147483
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:25216
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:303323
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:748
    KRAB; KRAB box
  14. NM_207333.4NP_997216.2  zinc finger protein 320 isoform 1

    See identical proteins and their annotated locations for NP_997216.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1). Variants 1-5 encode the same protein (isoform 1).
    Source sequence(s)
    AC010487, AI344388, AK096348, BC131555, DA025391, DA742339
    Consensus CDS
    CCDS33095.1
    UniProtKB/Swiss-Prot
    A2RRD8, Q8NDR6
    Conserved Domains (4) summary
    COG5048
    Location:147483
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:25216
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:303323
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:748
    KRAB; KRAB box

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    52859491..52904320 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024451397.2XP_024307165.1  zinc finger protein 320 isoform X2

    Conserved Domains (3) summary
    sd00017
    Location:155175
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:748
    KRAB; KRAB box
    pfam13465
    Location:168191
    zf-H2C2_2; Zinc-finger double domain
  2. XM_047438310.1XP_047294266.1  zinc finger protein 320 isoform X2

  3. XM_047438309.1XP_047294265.1  zinc finger protein 320 isoform X2

  4. XM_024451396.2XP_024307164.1  zinc finger protein 320 isoform X2

    Conserved Domains (3) summary
    sd00017
    Location:155175
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:748
    KRAB; KRAB box
    pfam13465
    Location:168191
    zf-H2C2_2; Zinc-finger double domain
  5. XM_047438305.1XP_047294261.1  zinc finger protein 320 isoform X1

    UniProtKB/Swiss-Prot
    Q8NDR6
  6. XM_047438308.1XP_047294264.1  zinc finger protein 320 isoform X1

    UniProtKB/Swiss-Prot
    Q8NDR6
  7. XM_047438306.1XP_047294262.1  zinc finger protein 320 isoform X1

    UniProtKB/Swiss-Prot
    Q8NDR6
  8. XM_047438302.1XP_047294258.1  zinc finger protein 320 isoform X1

    UniProtKB/Swiss-Prot
    Q8NDR6
  9. XM_047438301.1XP_047294257.1  zinc finger protein 320 isoform X1

    UniProtKB/Swiss-Prot
    Q8NDR6
  10. XM_047438307.1XP_047294263.1  zinc finger protein 320 isoform X1

    UniProtKB/Swiss-Prot
    Q8NDR6
  11. XM_047438300.1XP_047294256.1  zinc finger protein 320 isoform X1

    UniProtKB/Swiss-Prot
    Q8NDR6
  12. XM_047438303.1XP_047294259.1  zinc finger protein 320 isoform X1

    UniProtKB/Swiss-Prot
    Q8NDR6
  13. XM_047438304.1XP_047294260.1  zinc finger protein 320 isoform X1

    UniProtKB/Swiss-Prot
    Q8NDR6

RNA

  1. XR_002958275.2 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    55943802..55982216 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_024200.2: Suppressed sequence

    Description
    NG_024200.2: This RefSeq was removed because there is now support for transcription in this region.