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SLC16A11 solute carrier family 16 member 11 [ Homo sapiens (human) ]

Gene ID: 162515, updated on 28-Nov-2021

Summary

Official Symbol
SLC16A11provided by HGNC
Official Full Name
solute carrier family 16 member 11provided by HGNC
Primary source
HGNC:HGNC:23093
See related
Ensembl:ENSG00000174326 MIM:615765
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MCT11; MCT 11
Expression
Broad expression in kidney (RPKM 1.1), lung (RPKM 1.1) and 22 other tissues See more
Orthologs
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Genomic context

See SLC16A11 in Genome Data Viewer
Location:
17p13.1
Exon count:
5
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (7041621..7044411, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (6944940..6947411, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene BCL6B transcription repressor Neighboring gene solute carrier family 16 member 13 Neighboring gene C-type lectin domain containing 10A Neighboring gene asialoglycoprotein receptor 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ90193

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables monocarboxylic acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables pyruvate transmembrane transporter activity IDA
Inferred from Direct Assay
more info
PubMed 
enables symporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in lipid metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in monocarboxylic acid transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in pyruvate transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in integral component of membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
monocarboxylate transporter 11
Names
monocarboxylic acid transporter 11
solute carrier family 16 (monocarboxylic acid transporters), member 11

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001370549.1NP_001357478.1  monocarboxylate transporter 11 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC040977
    Related
    ENSP00000460927.2, ENST00000574600.3
    Conserved Domains (1) summary
    cl28910
    Location:14403
    MFS; Major Facilitator Superfamily
  2. NM_001370553.1NP_001357482.1  monocarboxylate transporter 11 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC040977
    Related
    ENSP00000501313.1, ENST00000673828.2
    Conserved Domains (1) summary
    cl28910
    Location:14372
    MFS; Major Facilitator Superfamily
  3. NM_153357.3NP_699188.2  monocarboxylate transporter 11 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC040977
    Consensus CDS
    CCDS11086.1
    Related
    ENSP00000499634.1, ENST00000662352.3
    Conserved Domains (1) summary
    cl28910
    Location:14403
    MFS; Major Facilitator Superfamily

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    7041621..7044411 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017024282.2XP_016879771.1  monocarboxylate transporter 11 isoform X3

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