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EML5 EMAP like 5 [ Homo sapiens (human) ]

Gene ID: 161436, updated on 21-Dec-2019

Summary

Official Symbol
EML5provided by HGNC
Official Full Name
EMAP like 5provided by HGNC
Primary source
HGNC:HGNC:18197
See related
Ensembl:ENSG00000165521 MIM:618119
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
EMAP-2; EMAP-5
Expression
Biased expression in ovary (RPKM 10.1), prostate (RPKM 3.2) and 12 other tissues See more
Orthologs

Genomic context

See EML5 in Genome Data Viewer
Location:
14q31.3
Exon count:
48
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 14 NC_000014.9 (88612148..88792953, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (89079241..89259096, complement)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene spermatogenesis associated 7 Neighboring gene protein tyrosine phosphatase non-receptor type 21 Neighboring gene uncharacterized LOC105370614 Neighboring gene RNA, U4 small nuclear 22, pseudogene Neighboring gene zinc finger CCCH-type containing 14 Neighboring gene RNA, U4 small nuclear 92, pseudogene Neighboring gene tetratricopeptide repeat domain 8

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • DKFZp781D1122

Gene Ontology Provided by GOA

Function Evidence Code Pubs
catalytic activity IEA
Inferred from Electronic Annotation
more info
 
microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
extracellular exosome HDA PubMed 
microtubule IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
echinoderm microtubule-associated protein-like 5
Names
echinoderm microtubule associated protein like 5

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_183387.3NP_899243.1  echinoderm microtubule-associated protein-like 5

    Status: VALIDATED

    Source sequence(s)
    AL121768, AL162171, BC032685, BC042055, BC150639
    Consensus CDS
    CCDS45148.1
    UniProtKB/Swiss-Prot
    Q05BV3
    Related
    ENSP00000451998.1, ENST00000554922.5
    Conserved Domains (4) summary
    COG2319
    Location:353843
    WD40; WD40 repeat [General function prediction only]
    pfam03451
    Location:547
    HELP; HELP motif
    sd00039
    Location:64104
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:7251063
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p13 Primary Assembly

    Range
    88612148..88792953 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017021065.2XP_016876554.1  echinoderm microtubule-associated protein-like 5 isoform X9

  2. XM_006720070.4XP_006720133.1  echinoderm microtubule-associated protein-like 5 isoform X7

    See identical proteins and their annotated locations for XP_006720133.1

    UniProtKB/Swiss-Prot
    Q05BV3
    Related
    ENSP00000370039.5, ENST00000380664.9
    Conserved Domains (4) summary
    COG2319
    Location:353843
    WD40; WD40 repeat [General function prediction only]
    pfam03451
    Location:547
    HELP; HELP motif
    sd00039
    Location:64104
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:7251063
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  3. XM_011536528.3XP_011534830.1  echinoderm microtubule-associated protein-like 5 isoform X1

    Conserved Domains (4) summary
    COG2319
    Location:353843
    WD40; WD40 repeat [General function prediction only]
    pfam03451
    Location:547
    HELP; HELP motif
    sd00039
    Location:64104
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:7251063
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  4. XM_011536533.3XP_011534835.1  echinoderm microtubule-associated protein-like 5 isoform X10

    Conserved Domains (4) summary
    COG2319
    Location:353891
    WD40; WD40 repeat [General function prediction only]
    pfam03451
    Location:547
    HELP; HELP motif
    sd00039
    Location:775814
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:7251025
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  5. XM_017021064.2XP_016876553.1  echinoderm microtubule-associated protein-like 5 isoform X8

  6. XM_011536531.3XP_011534833.1  echinoderm microtubule-associated protein-like 5 isoform X5

    Conserved Domains (4) summary
    COG2319
    Location:353843
    WD40; WD40 repeat [General function prediction only]
    pfam03451
    Location:547
    HELP; HELP motif
    sd00039
    Location:64104
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:7251063
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  7. XM_011536530.3XP_011534832.1  echinoderm microtubule-associated protein-like 5 isoform X2

    Conserved Domains (4) summary
    COG2319
    Location:353843
    WD40; WD40 repeat [General function prediction only]
    pfam03451
    Location:547
    HELP; HELP motif
    sd00039
    Location:64104
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:7251063
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  8. XM_017021063.2XP_016876552.1  echinoderm microtubule-associated protein-like 5 isoform X4

  9. XM_017021068.2XP_016876557.1  echinoderm microtubule-associated protein-like 5 isoform X13

  10. XM_011536532.3XP_011534834.1  echinoderm microtubule-associated protein-like 5 isoform X6

    Conserved Domains (4) summary
    COG2319
    Location:353843
    WD40; WD40 repeat [General function prediction only]
    pfam03451
    Location:547
    HELP; HELP motif
    sd00039
    Location:64104
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:7251063
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  11. XM_017021062.2XP_016876551.1  echinoderm microtubule-associated protein-like 5 isoform X3

  12. XM_017021066.2XP_016876555.1  echinoderm microtubule-associated protein-like 5 isoform X11

  13. XM_017021067.2XP_016876556.1  echinoderm microtubule-associated protein-like 5 isoform X12

  14. XM_011536534.3XP_011534836.1  echinoderm microtubule-associated protein-like 5 isoform X14

    Conserved Domains (4) summary
    COG2319
    Location:294784
    WD40; WD40 repeat [General function prediction only]
    pfam03451
    Location:612655
    HELP; HELP motif
    sd00039
    Location:745
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:6661004
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  15. XM_017021069.2XP_016876558.1  echinoderm microtubule-associated protein-like 5 isoform X14

    Conserved Domains (4) summary
    COG2319
    Location:294784
    WD40; WD40 repeat [General function prediction only]
    pfam03451
    Location:612655
    HELP; HELP motif
    sd00039
    Location:745
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:6661004
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  16. XM_011536536.2XP_011534838.1  echinoderm microtubule-associated protein-like 5 isoform X15

    Conserved Domains (4) summary
    COG2319
    Location:353843
    WD40; WD40 repeat [General function prediction only]
    pfam03451
    Location:547
    HELP; HELP motif
    sd00039
    Location:64104
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:7251063
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  17. XM_017021070.1XP_016876559.1  echinoderm microtubule-associated protein-like 5 isoform X16

  18. XM_011536538.3XP_011534840.1  echinoderm microtubule-associated protein-like 5 isoform X17

    Conserved Domains (4) summary
    COG2319
    Location:353843
    WD40; WD40 repeat [General function prediction only]
    pfam03451
    Location:547
    HELP; HELP motif
    sd00039
    Location:64104
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:7251026
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RNA

  1. XR_001750182.2 RNA Sequence

  2. XR_001750181.2 RNA Sequence

  3. XR_001750180.2 RNA Sequence

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