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Ighg2b immunoglobulin heavy constant gamma 2B [ Mus musculus (house mouse) ]

Gene ID: 16016, updated on 8-Jul-2021

Summary

Official Symbol
Ighg2bprovided by MGI
Official Full Name
immunoglobulin heavy constant gamma 2Bprovided by MGI
Primary source
MGI:MGI:96445
See related
Ensembl:ENSMUSG00000076613 IMGT/GENE-DB:IGHG2B
Gene type
other
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
IgG2; IgG2b; Igh-3; gamma2b
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Genomic context

See Ighg2b in Genome Data Viewer
Location:
12 F1; 12 62.1 cM
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (113267934..113271553, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (113304314..113307933, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (114542525..114546144, complement)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA40 Neighboring gene immunoglobulin heavy constant gamma 2C Neighboring gene Immunoglobulin heavy constant epsilon Neighboring gene immunoglobulin heavy constant gamma 1 (G1m marker) Neighboring gene immunoglobulin heavy chain complex

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Other Names

  • immunoglobulin heavy chain 3 (serum IgG2b)

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables antigen binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables antigen binding IDA
Inferred from Direct Assay
more info
PubMed 
enables immunoglobulin receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in B cell receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in complement activation, classical pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within complement activation, classical pathway IDA
Inferred from Direct Assay
more info
PubMed 
involved_in defense response to bacterium IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within humoral immune response mediated by circulating immunoglobulin IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within immunoglobulin mediated immune response IDA
Inferred from Direct Assay
more info
PubMed 
involved_in innate immune response IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in phagocytosis, engulfment IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within phagocytosis, engulfment IDA
Inferred from Direct Assay
more info
PubMed 
involved_in phagocytosis, recognition IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within phagocytosis, recognition IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of B cell activation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within positive regulation of immune response IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within positive regulation of phagocytosis IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within positive regulation of type I hypersensitivity IDA
Inferred from Direct Assay
more info
 
acts_upstream_of_or_within positive regulation of type IIa hypersensitivity IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in extracellular region TAS
Traceable Author Statement
more info
 
located_in extracellular space IDA
Inferred from Direct Assay
more info
PubMed 
located_in extracellular space ISO
Inferred from Sequence Orthology
more info
 
part_of immunoglobulin complex, circulating IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of immunoglobulin complex, circulating IDA
Inferred from Direct Assay
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_005838.1 

    Range
    56718..60337 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    113267934..113271553 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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