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Ier5 immediate early response 5 [ Mus musculus (house mouse) ]

Gene ID: 15939, updated on 24-Jan-2023


Official Symbol
Ier5provided by MGI
Official Full Name
immediate early response 5provided by MGI
Primary source
See related
Ensembl:ENSMUSG00000056708 AllianceGenome:MGI:1337072
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Predicted to enable identical protein binding activity. Predicted to be involved in several processes, including cellular response to heat; positive regulation of cellular response to heat; and positive regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm; nucleolus; and nucleoplasm. Predicted to be part of protein phosphatase type 2A complex. Is expressed in several structures, including branchial arch; central nervous system; forelimb bud; retina; and somite. Orthologous to human IER5 (immediate early response 5). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See Ier5 in Genome Data Viewer
1 G3; 1 66.45 cM
Exon count:
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (154972113..154975382, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (155096367..155099636, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 41980 Neighboring gene VISTA enhancer mm1694 Neighboring gene predicted gene, 41979 Neighboring gene predicted gene, 51651 Neighboring gene predicted gene 9530 Neighboring gene predicted gene, 41981 Neighboring gene predicted gene, 30922 Neighboring gene major histocompatibility complex, class I-related

Genomic regions, transcripts, and products



Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 


Products Interactant Other Gene Complex Source Pubs Description

General gene information



Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
located_in nucleus ISO
Inferred from Sequence Orthology
more info
part_of protein phosphatase type 2A complex ISO
Inferred from Sequence Orthology
more info

General protein information

Preferred Names
immediate early response gene 5 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010500.2NP_034630.1  immediate early response gene 5 protein

    See identical proteins and their annotated locations for NP_034630.1

    Status: VALIDATED

    Source sequence(s)
    AW913049, BC051986, BE200357, CJ064636, CX200138
    Consensus CDS
    O89113, Q8CGI0
    ENSMUSP00000056948.5, ENSMUST00000055322.6
    Conserved Domains (1) summary
    IER; Immediate early response protein (IER)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000067.7 Reference GRCm39 C57BL/6J

    154972113..154975382 complement
    GenBank, FASTA, Sequence Viewer (Graphics)