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SLC35G1 solute carrier family 35 member G1 [ Homo sapiens (human) ]

Gene ID: 159371, updated on 4-Jul-2021

Summary

Official Symbol
SLC35G1provided by HGNC
Official Full Name
solute carrier family 35 member G1provided by HGNC
Primary source
HGNC:HGNC:26607
See related
Ensembl:ENSG00000176273 MIM:617167
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
POST; TMEM20; C10orf60
Summary
This gene encodes a transmembrane protein which is a member of the drug/metabolite transporter protein superfamily. The encoded protein may play a role in the regulation of calcium levels inside the cell. [provided by RefSeq, Sep 2016]
Expression
Biased expression in duodenum (RPKM 26.1), small intestine (RPKM 12.8) and 2 other tissues See more
Orthologs
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Genomic context

See SLC35G1 in Genome Data Viewer
Location:
10q23.33
Exon count:
6
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (93893951..93914271)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (95653735..95669587)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105378437 Neighboring gene leucine rich glioma inactivated 1 Neighboring gene RAB11A, member RAS oncogene family pseudogene 1 Neighboring gene PIP5K1A and PSMD4 like (pseudogene) Neighboring gene uncharacterized LOC105378438

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ33990

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in integral component of membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
solute carrier family 35 member G1
Names
partner of STIM1
transmembrane protein 20

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_051626.1 RefSeqGene

    Range
    5009..14855
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001134658.3NP_001128130.1  solute carrier family 35 member G1 isoform 1

    See identical proteins and their annotated locations for NP_001128130.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AK091309, AL138923, BC041432, BC104814
    Consensus CDS
    CCDS44459.1
    UniProtKB/Swiss-Prot
    Q2M3R5
    Related
    ENSP00000400932.1, ENST00000427197.2
    Conserved Domains (1) summary
    COG0697
    Location:70359
    RhaT; Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only]
  2. NM_001345993.2NP_001332922.1  solute carrier family 35 member G1 isoform 3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. The encoded isoform (3) is shorter than isoform 1.
    Source sequence(s)
    AL138923, BC143283, DA644843
    UniProtKB/TrEMBL
    B7ZKP0
    Conserved Domains (1) summary
    COG0697
    Location:53342
    RhaT; Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only]
  3. NM_153226.4NP_694958.1  solute carrier family 35 member G1 isoform 2

    See identical proteins and their annotated locations for NP_694958.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the central coding region, compared to variant 1, resulting in a protein (isoform 2) that is one amino acid shorter than isoform 1.
    Source sequence(s)
    AK091309, AL138923, BC041432
    Consensus CDS
    CCDS7432.1
    UniProtKB/Swiss-Prot
    Q2M3R5
    Related
    ENSP00000360462.3, ENST00000371408.7
    Conserved Domains (2) summary
    COG0697
    Location:69358
    RhaT; Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only]
    pfam00892
    Location:68201
    EamA; EamA-like transporter family

RNA

  1. NR_144335.2 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) uses an alternate splice site in the 5'-terminal exon, and uses alternate internal and 3' exons, compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.
    Source sequence(s)
    AL138923, BC036382, DA644843
    Related
    ENST00000483386.5
  2. NR_144336.2 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) uses alternate internal and 3' exons, compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.
    Source sequence(s)
    AK091309, AL138923, BC047102, BM677569, BU608007, R56424
    Related
    ENST00000603665.1
  3. NR_144337.2 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) uses alternate internal and 3' exons, compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.
    Source sequence(s)
    AL138923

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

    Range
    93893951..93914271
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011539373.3XP_011537675.1  solute carrier family 35 member G1 isoform X1

    See identical proteins and their annotated locations for XP_011537675.1

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