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ZXDB zinc finger X-linked duplicated B [ Homo sapiens (human) ]

Gene ID: 158586, updated on 5-Sep-2021

Summary

Official Symbol
ZXDBprovided by HGNC
Official Full Name
zinc finger X-linked duplicated Bprovided by HGNC
Primary source
HGNC:HGNC:13199
See related
Ensembl:ENSG00000198455 MIM:300236
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZNF905; dJ83L6.1
Summary
The ZXDB gene is one of a pair of duplicated zinc finger genes on chromosome Xp11.21 (Greig et al., 1993 [PubMed 8268913]); see also ZXDA (MIM 300235).[supplied by OMIM, Jul 2010]
Orthologs
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Genomic context

See ZXDB in Genome Data Viewer
Location:
Xp11.21
Exon count:
1
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) X NC_000023.11 (57592011..57597477)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (57618444..57623910)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene fatty acid amide hydrolase 2 Neighboring gene protein phosphatase 1 regulatory inhibitor subunit 11 pseudogene 2 Neighboring gene methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 pseudogene 1 Neighboring gene uncharacterized LOC107985708 Neighboring gene NLR family pyrin domain containing 2B

Genomic regions, transcripts, and products

Phenotypes

Associated conditions

Description Tests
Genome-wide association study identifies loci affecting blood copper, selenium and zinc.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables transcription coregulator activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
zinc finger X-linked protein ZXDB

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007157.4NP_009088.1  zinc finger X-linked protein ZXDB

    See identical proteins and their annotated locations for NP_009088.1

    Status: REVIEWED

    Source sequence(s)
    AL031115
    Consensus CDS
    CCDS35313.1
    UniProtKB/Swiss-Prot
    P98169
    Related
    ENSP00000364023.1, ENST00000374888.3
    Conserved Domains (6) summary
    COG5048
    Location:441572
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:429448
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:516538
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:304328
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:350373
    zf-H2C2_2; Zinc-finger double domain
    pfam17017
    Location:304449
    zf-C2H2_aberr; Aberrant zinc-finger

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p13 Primary Assembly

    Range
    57592011..57597477
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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