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TSTD2 thiosulfate sulfurtransferase like domain containing 2 [ Homo sapiens (human) ]

Gene ID: 158427, updated on 6-Nov-2022

Summary

Official Symbol
TSTD2provided by HGNC
Official Full Name
thiosulfate sulfurtransferase like domain containing 2provided by HGNC
Primary source
HGNC:HGNC:30087
See related
Ensembl:ENSG00000136925 AllianceGenome:HGNC:30087
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C9orf97
Expression
Ubiquitous expression in heart (RPKM 18.5), adrenal (RPKM 16.8) and 25 other tissues See more
Orthologs
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Genomic context

See TSTD2 in Genome Data Viewer
Location:
9q22.33
Exon count:
10
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (97600080..97633368, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (109772021..109805309, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (100362362..100395650, complement)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105376168 Neighboring gene tropomodulin 1 Neighboring gene Sharpr-MPRA regulatory region 7780 Neighboring gene Sharpr-MPRA regulatory region 9871 Neighboring gene nuclear cap binding protein subunit 1 Neighboring gene XPA, DNA damage recognition and repair factor

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

EBI GWAS Catalog

Description
The FOXE1 locus is a major genetic determinant for radiation-related thyroid carcinoma in Chernobyl.
EBI GWAS Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ36724

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2
Names
PP4189
rhodanese domain-containing protein 2
rhodanese like domain containing 2
thiosulfate sulfurtransferase (rhodanese)-like domain containing 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_139246.5NP_640339.4  thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2

    See identical proteins and their annotated locations for NP_640339.4

    Status: VALIDATED

    Source sequence(s)
    AL162385, BC035604, BU625565, CN298691, DA735730
    Consensus CDS
    CCDS6727.2
    UniProtKB/Swiss-Prot
    Q5T7W7, Q96MU1
    Related
    ENSP00000342499.4, ENST00000341170.5
    Conserved Domains (3) summary
    PRK00142
    Location:170484
    PRK00142; putative rhodanese-related sulfurtransferase; Provisional
    cd01518
    Location:279389
    RHOD_YceA; Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins.
    pfam12368
    Location:398460
    Rhodanese_C; Rhodanase C-terminal

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    97600080..97633368 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    109772021..109805309 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)