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TTC16 tetratricopeptide repeat domain 16 [ Homo sapiens (human) ]

Gene ID: 158248, updated on 23-Nov-2021

Summary

Official Symbol
TTC16provided by HGNC
Official Full Name
tetratricopeptide repeat domain 16provided by HGNC
Primary source
HGNC:HGNC:26536
See related
Ensembl:ENSG00000167094
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Biased expression in testis (RPKM 9.1), lung (RPKM 0.9) and 2 other tissues See more
Orthologs
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Genomic context

See TTC16 in Genome Data Viewer
Location:
9q34.11
Exon count:
16
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 9 NC_000009.12 (127716064..127731590)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (130478358..130493869)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene syntaxin binding protein 1 Neighboring gene microRNA 3911 Neighboring gene peptidyl-tRNA hydrolase 1 homolog Neighboring gene cilia and flagella associated protein 157 Neighboring gene Sharpr-MPRA regulatory region 4083 Neighboring gene torsin family 2 member A Neighboring gene SH2 domain containing 3C Neighboring gene uncharacterized LOC107987132

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ32780

General protein information

Preferred Names
tetratricopeptide repeat protein 16
Names
TPR repeat protein 16

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001317037.2NP_001303966.1  tetratricopeptide repeat protein 16 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice junction in the 5' end compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
    Source sequence(s)
    AK057342, AK302737
    UniProtKB/Swiss-Prot
    Q8NEE8
    UniProtKB/TrEMBL
    B4DH05, B4DZ42
    Conserved Domains (4) summary
    sd00006
    Location:320346
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:355385
    TPR_1; Tetratricopeptide repeat
    pfam05338
    Location:71130
    DUF717; Protein of unknown function (DUF717)
    pfam13414
    Location:319383
    TPR_11; TPR repeat
  2. NM_144965.3NP_659402.1  tetratricopeptide repeat protein 16 isoform 1

    See identical proteins and their annotated locations for NP_659402.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AK057342
    Consensus CDS
    CCDS6875.1
    UniProtKB/Swiss-Prot
    Q8NEE8
    UniProtKB/TrEMBL
    B4DH05
    Related
    ENSP00000362386.3, ENST00000373289.4
    Conserved Domains (3) summary
    sd00006
    Location:333359
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:368398
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:62124
    TPR_11; TPR repeat

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p13 Primary Assembly

    Range
    127716064..127731590
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011518292.2XP_011516594.1  tetratricopeptide repeat protein 16 isoform X7

    See identical proteins and their annotated locations for XP_011516594.1

    Conserved Domains (2) summary
    PHA03247
    Location:40292
    PHA03247; large tegument protein UL36; Provisional
    COG5099
    Location:391569
    COG5099; RNA-binding protein of the Puf family, translational repressor [Translation, ribosomal structure and biogenesis]
  2. XM_011518284.2XP_011516586.1  tetratricopeptide repeat protein 16 isoform X2

    Conserved Domains (4) summary
    COG0457
    Location:70348
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:285311
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:320350
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:319389
    TPR_11; TPR repeat
  3. XM_011518288.2XP_011516590.1  tetratricopeptide repeat protein 16 isoform X4

    Conserved Domains (3) summary
    sd00006
    Location:156184
    TPR; TPR repeat [structural motif]
    pfam13371
    Location:212277
    TPR_9; Tetratricopeptide repeat
    pfam13414
    Location:62119
    TPR_11; TPR repeat
  4. XM_011518290.2XP_011516592.1  tetratricopeptide repeat protein 16 isoform X6

    See identical proteins and their annotated locations for XP_011516592.1

    Conserved Domains (3) summary
    sd00006
    Location:155181
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:190220
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:154218
    TPR_11; TPR repeat
  5. XM_011518291.2XP_011516593.1  tetratricopeptide repeat protein 16 isoform X7

    See identical proteins and their annotated locations for XP_011516593.1

    Conserved Domains (2) summary
    PHA03247
    Location:40292
    PHA03247; large tegument protein UL36; Provisional
    COG5099
    Location:391569
    COG5099; RNA-binding protein of the Puf family, translational repressor [Translation, ribosomal structure and biogenesis]
  6. XM_005251734.2XP_005251791.1  tetratricopeptide repeat protein 16 isoform X8

    Conserved Domains (2) summary
    sd00006
    Location:222252
    TPR; TPR repeat [structural motif]
    pfam13414
    Location:202254
    TPR_11; TPR repeat
  7. XM_011518285.2XP_011516587.1  tetratricopeptide repeat protein 16 isoform X3

    Conserved Domains (4) summary
    sd00006
    Location:6189
    TPR; TPR repeat [structural motif]
    cd15830
    Location:61149
    BamD; BamD lipoprotein, a component of the beta-barrel assembly machinery
    pfam13371
    Location:260325
    TPR_9; Tetratricopeptide repeat
    pfam13414
    Location:62124
    TPR_11; TPR repeat
  8. XM_006716970.2XP_006717033.1  tetratricopeptide repeat protein 16 isoform X6

    See identical proteins and their annotated locations for XP_006717033.1

    Conserved Domains (3) summary
    sd00006
    Location:155181
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:190220
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:154218
    TPR_11; TPR repeat
  9. XM_005251733.2XP_005251790.1  tetratricopeptide repeat protein 16 isoform X5

    Conserved Domains (3) summary
    sd00006
    Location:157183
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:192222
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:156220
    TPR_11; TPR repeat
  10. XM_006716971.2XP_006717034.1  tetratricopeptide repeat protein 16 isoform X6

    See identical proteins and their annotated locations for XP_006717034.1

    Conserved Domains (3) summary
    sd00006
    Location:155181
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:190220
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:154218
    TPR_11; TPR repeat
  11. XM_011518283.2XP_011516585.1  tetratricopeptide repeat protein 16 isoform X1

    Conserved Domains (3) summary
    sd00006
    Location:333359
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:368398
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:62124
    TPR_11; TPR repeat
  12. XM_011518293.2XP_011516595.1  tetratricopeptide repeat protein 16 isoform X9

    Conserved Domains (3) summary
    sd00006
    Location:333359
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:368398
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:62124
    TPR_11; TPR repeat
  13. XM_011518295.2XP_011516597.1  tetratricopeptide repeat protein 16 isoform X11

    Conserved Domains (3) summary
    sd00006
    Location:333359
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:368398
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:62124
    TPR_11; TPR repeat
  14. XM_011518294.3XP_011516596.1  tetratricopeptide repeat protein 16 isoform X10

    Conserved Domains (3) summary
    sd00006
    Location:333359
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:368398
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:62124
    TPR_11; TPR repeat
  15. XM_011518297.2XP_011516599.1  tetratricopeptide repeat protein 16 isoform X12

    Conserved Domains (3) summary
    sd00006
    Location:333359
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:368398
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:62124
    TPR_11; TPR repeat
  16. XM_011518298.3XP_011516600.1  tetratricopeptide repeat protein 16 isoform X13

    Conserved Domains (3) summary
    sd00006
    Location:6189
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:368398
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:62124
    TPR_11; TPR repeat
  17. XM_011518289.3XP_011516591.1  tetratricopeptide repeat protein 16 isoform X6

    See identical proteins and their annotated locations for XP_011516591.1

    Conserved Domains (3) summary
    sd00006
    Location:155181
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:190220
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:154218
    TPR_11; TPR repeat

RNA

  1. XR_002956761.1 RNA Sequence

  2. XR_929722.2 RNA Sequence

  3. XR_001746193.2 RNA Sequence

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