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TDRP testis development related protein [ Homo sapiens (human) ]

Gene ID: 157695, updated on 5-Aug-2022

Summary

Official Symbol
TDRPprovided by HGNC
Official Full Name
testis development related proteinprovided by HGNC
Primary source
HGNC:HGNC:26951
See related
Ensembl:ENSG00000180190 MIM:619049; AllianceGenome:HGNC:26951
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Inm01; TDRP1; TDRP2; C8orf42
Summary
Acts upstream of or within spermatogenesis. Located in cytosol and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in placenta (RPKM 17.5), thyroid (RPKM 13.8) and 22 other tissues See more
Orthologs
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Try the new Transcript table

Genomic context

See TDRP in Genome Data Viewer
Location:
8p23.3
Exon count:
5
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (489946..545780, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (287190..342875, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (439946..495780, complement)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 87 member A Neighboring gene F-box protein 25 Neighboring gene uncharacterized LOC124902055 Neighboring gene glutamate rich 1 Neighboring gene uncharacterized LOC124902053

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

EBI GWAS Catalog

Description
Mayo Genome Consortia: a genotype-phenotype resource for genome-wide association studies with an application to the analysis of circulating bilirubin levels.
EBI GWAS Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ44221, DKFZp686J15216

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in spermatogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within spermatogenesis IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
 
located_in intracellular membrane-bounded organelle IDA
Inferred from Direct Assay
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
testis development-related protein

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001256113.2NP_001243042.1  testis development-related protein isoform 2

    See identical proteins and their annotated locations for NP_001243042.1

    Status: VALIDATED

    Source sequence(s)
    AC083964, AC090135
    Consensus CDS
    CCDS59090.1
    UniProtKB/Swiss-Prot
    Q86YL5
    Related
    ENSP00000430325.1, ENST00000523656.5
    Conserved Domains (1) summary
    pfam15683
    Location:41167
    TDRP; Testis development-related protein
  2. NM_001384899.1NP_001371828.1  testis development-related protein isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC083964, AC090135
    UniProtKB/Swiss-Prot
    B9EG53
    Related
    ENSP00000315111.6, ENST00000324079.11
    Conserved Domains (1) summary
    pfam15683
    Location:41185
    TDRP; Testis development-related protein
  3. NM_175075.5NP_778250.2  testis development-related protein isoform 1

    See identical proteins and their annotated locations for NP_778250.2

    Status: VALIDATED

    Source sequence(s)
    AC083964, AC090135, AC090691
    Consensus CDS
    CCDS47759.1
    UniProtKB/Swiss-Prot
    B9EG53, Q86YL5
    Conserved Domains (1) summary
    pfam15683
    Location:41185
    TDRP; Testis development-related protein

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

    Range
    489946..545780 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047421392.1XP_047277348.1  testis development-related protein isoform X1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060932.1 Alternate T2T-CHM13v2.0

    Range
    287190..342875 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001369716.1: Suppressed sequence

    Description
    NM_001369716.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.