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TMEM65 transmembrane protein 65 [ Homo sapiens (human) ]

Gene ID: 157378, updated on 13-Mar-2020

Summary

Official Symbol
TMEM65provided by HGNC
Official Full Name
transmembrane protein 65provided by HGNC
Primary source
HGNC:HGNC:25203
See related
Ensembl:ENSG00000164983 MIM:616609
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in duodenum (RPKM 11.1), brain (RPKM 8.4) and 25 other tissues See more
Orthologs

Genomic context

See TMEM65 in Genome Data Viewer
Location:
8q24.13
Exon count:
7
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 8 NC_000008.11 (124310918..124372699, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (125323159..125384940, complement)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107986973 Neighboring gene RNA, U6 small nuclear 756, pseudogene Neighboring gene transcription factor SOX-2-like Neighboring gene Sharpr-MPRA regulatory region 2045 Neighboring gene RNF139 antisense RNA 1 (head to head) Neighboring gene tRNA methyltransferase 12 homolog

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ37785

Gene Ontology Provided by GOA

Process Evidence Code Pubs
cardiac ventricle development ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of cardiac conduction ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
intercalated disc IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrial inner membrane IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_194291.2NP_919267.2  transmembrane protein 65

    See identical proteins and their annotated locations for NP_919267.2

    Status: VALIDATED

    Source sequence(s)
    AC090192, AW300050, BC032396, BM679703, BQ433192, DB479586
    Consensus CDS
    CCDS6348.1
    UniProtKB/Swiss-Prot
    Q6PI78
    Related
    ENSP00000297632.6, ENST00000297632.7
    Conserved Domains (1) summary
    pfam10507
    Location:120227
    DUF2453; Protein of unknown function (DUF2453)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p13 Primary Assembly

    Range
    124310918..124372699 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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