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Elavl3 ELAV like RNA binding protein 3 [ Mus musculus (house mouse) ]

Gene ID: 15571, updated on 10-Jan-2023

Summary

Official Symbol
Elavl3provided by MGI
Official Full Name
ELAV like RNA binding protein 3provided by MGI
Primary source
MGI:MGI:109157
See related
Ensembl:ENSMUSG00000003410 AllianceGenome:MGI:109157
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Huc; mHuC; PLE21; 2600009P04Rik
Summary
Enables mRNA 3'-UTR AU-rich region binding activity. Predicted to act upstream of or within cell differentiation and nervous system development. Predicted to be part of ribonucleoprotein complex. Is expressed in central nervous system; enteric nervous system; intestine; primitive bladder; and sensory organ. Orthologous to human ELAVL3 (ELAV like RNA binding protein 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in CNS E18 (RPKM 68.0), whole brain E14.5 (RPKM 67.5) and 5 other tissues See more
Orthologs
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Genomic context

See Elavl3 in Genome Data Viewer
Location:
9 A3; 9 8.07 cM
Exon count:
7
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (21926301..21963442, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (22015005..22052146, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 36414 Neighboring gene outer dynein arm docking complex subunit 3 Neighboring gene protein kinase C substrate 80K-H Neighboring gene zinc finger protein 653 Neighboring gene predicted gene, 16845 Neighboring gene ECSIT signalling integrator

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables mRNA 3'-UTR AU-rich region binding IDA
Inferred from Direct Assay
more info
PubMed 
enables mRNA 3'-UTR AU-rich region binding ISO
Inferred from Sequence Orthology
more info
 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within nervous system development IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ELAV-like protein 3
Names
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)
HU-antigen C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010487.2NP_034617.1  ELAV-like protein 3

    See identical proteins and their annotated locations for NP_034617.1

    Status: VALIDATED

    Source sequence(s)
    AC163623, AK090281, BC052097
    Consensus CDS
    CCDS52741.1
    UniProtKB/Swiss-Prot
    Q60900, Q60901
    UniProtKB/TrEMBL
    A0A6P5QIS9, A0A8C6H4D6
    Related
    ENSMUSP00000003501.8, ENSMUST00000003501.9
    Conserved Domains (1) summary
    TIGR01661
    Location:36366
    ELAV_HUD_SF; ELAV/HuD family splicing factor

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    21926301..21963442 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006510022.2XP_006510085.1  ELAV-like protein 3 isoform X2

    See identical proteins and their annotated locations for XP_006510085.1

    UniProtKB/Swiss-Prot
    Q60900
    UniProtKB/TrEMBL
    A0A6P7RE62
    Conserved Domains (1) summary
    TIGR01661
    Location:36359
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  2. XM_030244064.1XP_030099924.1  ELAV-like protein 3 isoform X3

    Conserved Domains (1) summary
    TIGR01661
    Location:35358
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  3. XM_006510021.2XP_006510084.1  ELAV-like protein 3 isoform X1

    See identical proteins and their annotated locations for XP_006510084.1

    UniProtKB/TrEMBL
    A0A6P7R9L1
    Conserved Domains (1) summary
    TIGR01661
    Location:35365
    ELAV_HUD_SF; ELAV/HuD family splicing factor