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Htr6 5-hydroxytryptamine (serotonin) receptor 6 [ Mus musculus (house mouse) ]

Gene ID: 15565, updated on 6-Aug-2017
Official Symbol
Htr6provided by MGI
Official Full Name
5-hydroxytryptamine (serotonin) receptor 6provided by MGI
Primary source
MGI:MGI:1196627
See related
Ensembl:ENSMUSG00000028747 Vega:OTTMUSG00000009899
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
5-HT6
Orthologs
Location:
4 D3; 4 70.57 cM
Exon count:
4
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (139059705..139075521, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (138617324..138630704, complement)

Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene ring finger protein 186 Neighboring gene transmembrane and coiled-coil domains 4 Neighboring gene predicted gene, 33214 Neighboring gene predicted gene 45533 Neighboring gene neuroblastoma, suppression of tumorigenicity 1 Neighboring gene mitochondrial inner membrane organizing system 1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC144682, MGC144683

Gene Ontology Provided by MGI

Function Evidence Code Pubs
G-protein coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
G-protein coupled serotonin receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
G-protein coupled serotonin receptor activity ISO
Inferred from Sequence Orthology
more info
 
neurotransmitter receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
signal transducer activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
G-protein coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger ISO
Inferred from Sequence Orthology
more info
 
cerebral cortex cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
learning ISO
Inferred from Sequence Orthology
more info
 
long-term synaptic potentiation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of acetylcholine secretion, neurotransmission ISO
Inferred from Sequence Orthology
more info
 
negative regulation of gamma-aminobutyric acid secretion ISO
Inferred from Sequence Orthology
more info
 
negative regulation of glutamate secretion ISO
Inferred from Sequence Orthology
more info
 
positive regulation of TOR signaling IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of TOR signaling ISO
Inferred from Sequence Orthology
more info
 
positive regulation of dopamine secretion ISO
Inferred from Sequence Orthology
more info
 
positive regulation of gamma-aminobutyric acid secretion ISO
Inferred from Sequence Orthology
more info
 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cilium IDA
Inferred from Direct Assay
more info
PubMed 
dendrite ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
5-hydroxytryptamine receptor 6
Names
5-HT-6
serotonin receptor 6

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_021358.2NP_067333.1  5-hydroxytryptamine receptor 6

    See identical proteins and their annotated locations for NP_067333.1

    Status: PROVISIONAL

    Source sequence(s)
    AL805923
    Consensus CDS
    CCDS18838.1
    UniProtKB/Swiss-Prot
    Q9R1C8
    UniProtKB/TrEMBL
    Q14AW8
    Related
    ENSMUSP00000068333.1, ENSMUST00000068036.1
    Conserved Domains (1) summary
    pfam00001
    Location:44322
    7tm_1; 7 transmembrane receptor (rhodopsin family)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

    Range
    139059705..139075521 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011250196.2XP_011248498.1  5-hydroxytryptamine receptor 6 isoform X1

    See identical proteins and their annotated locations for XP_011248498.1

    UniProtKB/Swiss-Prot
    Q9R1C8
    UniProtKB/TrEMBL
    Q14AW8
    Related
    ENSMUSP00000101428.1, OTTMUSP00000010478, ENSMUST00000105802.7, OTTMUST00000022954
    Conserved Domains (1) summary
    pfam00001
    Location:44322
    7tm_1; 7 transmembrane receptor (rhodopsin family)
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