Format

Send to:

Choose Destination

Htr1d 5-hydroxytryptamine (serotonin) receptor 1D [ Mus musculus (house mouse) ]

Gene ID: 15552, updated on 23-May-2018
Official Symbol
Htr1dprovided by MGI
Official Full Name
5-hydroxytryptamine (serotonin) receptor 1Dprovided by MGI
Primary source
MGI:MGI:96276
See related
Ensembl:ENSMUSG00000070687 Vega:OTTMUSG00000009699
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
5-HT1D; Gpcr14; Htr1db; 5-HT-1D; AI853647
Expression
Biased expression in ovary adult (RPKM 1.0), bladder adult (RPKM 0.8) and 12 other tissues See more
Orthologs
See Htr1d in Genome Data Viewer
Location:
4 D3; 4 68.74 cM
Exon count:
5
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (136423522..136444405)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (135979439..136000317)

Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 9130020K20 gene Neighboring gene predicted gene, 31295 Neighboring gene leucine zipper protein 1 Neighboring gene lysine (K)-specific demethylase 1A Neighboring gene heterogeneous nuclear ribonucleoprotein A3 pseudogene Neighboring gene testis expressed 46

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (3) 

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
G-protein coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
G-protein coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
G-protein coupled serotonin receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
G-protein coupled serotonin receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
G-protein coupled serotonin receptor activity ISO
Inferred from Sequence Orthology
more info
 
neurotransmitter receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
serotonin binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
G-protein coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
chemical synaptic transmission IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 
intestine smooth muscle contraction ISO
Inferred from Sequence Orthology
more info
 
regulation of behavior IEA
Inferred from Electronic Annotation
more info
 
regulation of locomotion IEA
Inferred from Electronic Annotation
more info
 
response to toxic substance IDA
Inferred from Direct Assay
more info
PubMed 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
smooth muscle contraction IEA
Inferred from Electronic Annotation
more info
 
vasoconstriction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
dendrite IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
5-hydroxytryptamine receptor 1D
Names
5-hydroxytryptamine (serotonin) receptor 1D beta
G-protein coupled receptor 14
serotonin receptor 1D

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001285482.1NP_001272411.1  5-hydroxytryptamine receptor 1D

    See identical proteins and their annotated locations for NP_001272411.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2, 3 and 4 all encode the same protein.
    Source sequence(s)
    AI853647, AK082016, AL670673, AW487918, BY728591
    Consensus CDS
    CCDS18806.1
    UniProtKB/Swiss-Prot
    Q61224
    Related
    ENSMUSP00000112402.1, OTTMUSP00000036225, ENSMUST00000121571.7, OTTMUST00000022403
    Conserved Domains (1) summary
    pfam00001
    Location:53353
    7tm_1; 7 transmembrane receptor (rhodopsin family)
  2. NM_001285483.1NP_001272412.1  5-hydroxytryptamine receptor 1D

    See identical proteins and their annotated locations for NP_001272412.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3 and 4 all encode the same protein.
    Source sequence(s)
    AI853647, AK082016, AL670673, AW487918
    Consensus CDS
    CCDS18806.1
    UniProtKB/Swiss-Prot
    Q61224
    Related
    ENSMUSP00000112840.1, OTTMUSP00000036224, ENSMUST00000117699.1, OTTMUST00000070934
    Conserved Domains (1) summary
    pfam00001
    Location:53353
    7tm_1; 7 transmembrane receptor (rhodopsin family)
  3. NM_001285484.1NP_001272413.1  5-hydroxytryptamine receptor 1D

    See identical proteins and their annotated locations for NP_001272413.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3 and 4 all encode the same protein.
    Source sequence(s)
    AI853647, AK082016, AL670673, AW487918
    Consensus CDS
    CCDS18806.1
    UniProtKB/Swiss-Prot
    Q61224
    Conserved Domains (1) summary
    pfam00001
    Location:53353
    7tm_1; 7 transmembrane receptor (rhodopsin family)
  4. NM_008309.5NP_032335.2  5-hydroxytryptamine receptor 1D

    See identical proteins and their annotated locations for NP_032335.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3 and 4 all encode the same protein.
    Source sequence(s)
    AI853647, AK082016, AW487918, BY728591
    Consensus CDS
    CCDS18806.1
    UniProtKB/Swiss-Prot
    Q61224
    Related
    ENSMUSP00000086052.4, OTTMUSP00000010214, ENSMUST00000088677.4, OTTMUST00000022402
    Conserved Domains (1) summary
    pfam00001
    Location:53353
    7tm_1; 7 transmembrane receptor (rhodopsin family)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

    Range
    136423522..136444405
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006538578.2XP_006538641.1  5-hydroxytryptamine receptor 1D isoform X1

    See identical proteins and their annotated locations for XP_006538641.1

    UniProtKB/Swiss-Prot
    Q61224
    Conserved Domains (1) summary
    pfam00001
    Location:53353
    7tm_1; 7 transmembrane receptor (rhodopsin family)
  2. XM_017319986.1XP_017175475.1  5-hydroxytryptamine receptor 1D isoform X1

    UniProtKB/Swiss-Prot
    Q61224
    Conserved Domains (1) summary
    pfam00001
    Location:53353
    7tm_1; 7 transmembrane receptor (rhodopsin family)
  3. XM_006538577.2XP_006538640.1  5-hydroxytryptamine receptor 1D isoform X1

    See identical proteins and their annotated locations for XP_006538640.1

    UniProtKB/Swiss-Prot
    Q61224
    Conserved Domains (1) summary
    pfam00001
    Location:53353
    7tm_1; 7 transmembrane receptor (rhodopsin family)
Support Center