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GIMAP8 GTPase, IMAP family member 8 [ Homo sapiens (human) ]

Gene ID: 155038, updated on 25-Jan-2022

Summary

Official Symbol
GIMAP8provided by HGNC
Official Full Name
GTPase, IMAP family member 8provided by HGNC
Primary source
HGNC:HGNC:21792
See related
Ensembl:ENSG00000171115 MIM:616962; AllianceGenome:HGNC:21792
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
IAN6; IAN9; IANT; IAN-9
Summary
This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. [provided by RefSeq, Jul 2008]
Expression
Broad expression in spleen (RPKM 22.2), lung (RPKM 17.5) and 22 other tissues See more
Orthologs
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Genomic context

See GIMAP8 in Genome Data Viewer
Location:
7q36.1
Exon count:
6
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (150450630..150479395)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (150147718..150176481)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107986859 Neighboring gene zinc finger domain-containing protein LOC728743 Neighboring gene long intergenic non-protein coding RNA 996 Neighboring gene eukaryotic translation initiation factor 2A pseudogene 1 Neighboring gene STE20-related kinase adaptor beta pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC129545, DKFZp667I133

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in regulation of T cell apoptotic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
GTPase IMAP family member 8
Names
human immune associated nucleotide 6
immune-associated nucleotide-binding protein 9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175571.4NP_783161.1  GTPase IMAP family member 8

    See identical proteins and their annotated locations for NP_783161.1

    Status: REVIEWED

    Source sequence(s)
    AL834361, BC107037, DA241971
    Consensus CDS
    CCDS34777.1
    UniProtKB/Swiss-Prot
    Q8ND71
    UniProtKB/TrEMBL
    A0A090N8H2
    Related
    ENSP00000305107.3, ENST00000307271.4
    Conserved Domains (1) summary
    cd01852
    Location:439638
    AIG1; AvrRpt2-Induced Gene 1 (AIG1)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    150450630..150479395
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005249951.4XP_005250008.1  GTPase IMAP family member 8 isoform X2

    Conserved Domains (1) summary
    cd01852
    Location:230429
    AIG1; AvrRpt2-Induced Gene 1 (AIG1)
  2. XM_005249950.4XP_005250007.1  GTPase IMAP family member 8 isoform X1

    See identical proteins and their annotated locations for XP_005250007.1

    UniProtKB/Swiss-Prot
    Q8ND71
    UniProtKB/TrEMBL
    A0A090N8H2
    Conserved Domains (1) summary
    cd01852
    Location:439638
    AIG1; AvrRpt2-Induced Gene 1 (AIG1)
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