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Hoxb9 homeobox B9 [ Mus musculus (house mouse) ]

Gene ID: 15417, updated on 5-Mar-2024

Summary

Official Symbol
Hoxb9provided by MGI
Official Full Name
homeobox B9provided by MGI
Primary source
MGI:MGI:96190
See related
Ensembl:ENSMUSG00000020875 AllianceGenome:MGI:96190
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Hox-2.5
Summary
Contributes to RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including embryonic skeletal system development; mammary gland development; and positive regulation of transcription by RNA polymerase II. Part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including early embryo; embryo mesenchyme; genitourinary system; gut; and nervous system. Orthologous to human HOXB9 (homeobox B9). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in adrenal adult (RPKM 78.5), colon adult (RPKM 12.4) and 3 other tissues See more
Orthologs
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Genomic context

See Hoxb9 in Genome Data Viewer
Location:
11 D; 11 59.81 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (96162156..96167421)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (96271330..96276595)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_30544 Neighboring gene predicted gene 53 Neighboring gene microRNA 196a-1 Neighboring gene predicted gene, 51876 Neighboring gene homeobox B8 Neighboring gene homeobox B7

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1)  1 citation
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC124051, MGC124052, MGC124053, MGC124054

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 
involved_in anterior/posterior pattern specification IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within anterior/posterior pattern specification IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within anterior/posterior pattern specification IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cell chemotaxis ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within embryonic skeletal system development IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within embryonic skeletal system development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in embryonic skeletal system morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within mammary gland development IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
involved_in proximal/distal pattern formation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of RNA polymerase II transcription regulator complex IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
homeobox protein Hox-B9
Names
homeo box B9
homeobox protein Hox-2.5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008270.2NP_032296.2  homeobox protein Hox-B9

    See identical proteins and their annotated locations for NP_032296.2

    Status: VALIDATED

    Source sequence(s)
    AA386586, AI116698, AL645478
    Consensus CDS
    CCDS25292.1
    UniProtKB/Swiss-Prot
    A2A9Z6, P20615
    Related
    ENSMUSP00000000010.9, ENSMUST00000000010.9
    Conserved Domains (2) summary
    pfam00046
    Location:188242
    Homeobox; Homeobox domain
    pfam04617
    Location:1172
    Hox9_act; Hox9 activation region

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    96162156..96167421
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)