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HDGFL1 HDGF like 1 [ Homo sapiens (human) ]

Gene ID: 154150, updated on 11-Jun-2021

Summary

Official Symbol
HDGFL1provided by HGNC
Official Full Name
HDGF like 1provided by HGNC
Primary source
HGNC:HGNC:21095
See related
Ensembl:ENSG00000112273
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HRP-1; PWWP1; Hdgfrp1; dJ309H15.1
Orthologs
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Genomic context

See HDGFL1 in Genome Data Viewer
Location:
6p22.3
Exon count:
1
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 6 NC_000006.12 (22569566..22571666)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (22569795..22571895)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene cancer susceptibility 15 Neighboring gene VISTA enhancer hs1335 Neighboring gene uncharacterized LOC105374971 Neighboring gene prolactin Neighboring gene uncharacterized LOC105374972 Neighboring gene uncharacterized LOC105374973 Neighboring gene uncharacterized LOC102724736

Genomic regions, transcripts, and products

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables double-stranded DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables transcription coregulator activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
hepatoma-derived growth factor-like protein 1
Names
HDGF (hepatoma-derived growth factor) like
PWWP domain containing 1
PWWP domain-containing protein 1
hepatoma derived growth factor-like 1
testicular tissue protein Li 84

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_138574.4NP_612641.2  hepatoma-derived growth factor-like protein 1

    See identical proteins and their annotated locations for NP_612641.2

    Status: VALIDATED

    Source sequence(s)
    AL033539
    Consensus CDS
    CCDS34347.1
    UniProtKB/Swiss-Prot
    Q5TGJ6
    UniProtKB/TrEMBL
    A0A140VJK8
    Related
    ENSP00000442129.1, ENST00000510882.4
    Conserved Domains (2) summary
    cd05834
    Location:985
    HDGF_related; The PWWP domain is an essential part of the Hepatoma Derived Growth Factor (HDGF) family of proteins, and is necessary for DNA binding by HDGF. This family of endogenous nuclear-targeted mitogens includes HRP (HDGF-related proteins 1, 2, 3, 4, or HPR1, ...
    PHA00666
    Location:81159
    PHA00666; putative protease

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p13 Primary Assembly

    Range
    22569566..22571666
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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