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Hoxb1 homeobox B1 [ Mus musculus (house mouse) ]

Gene ID: 15407, updated on 25-Jun-2019

Summary

Official Symbol
Hoxb1provided by MGI
Official Full Name
homeobox B1provided by MGI
Primary source
MGI:MGI:96182
See related
Ensembl:ENSMUSG00000018973
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Hox-2.9
Expression
Low expression observed in reference dataset See more
Orthologs

Genomic context

See Hoxb1 in Genome Data Viewer
Location:
11 D; 11 59.86 cM
Exon count:
2
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (96365746..96368254)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (96227072..96229567)

Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene homeobox B3 Neighboring gene homeobox B4 Neighboring gene homeobox B3 and homeobox B2, opposite strand Neighboring gene homeobox B2 Neighboring gene ribosomal protein L17 pseudogene Neighboring gene predicted gene 11529

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (14)  1 citation
  • Chemically induced (ENU) (1) 

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC124123

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
contributes_to DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
DNA binding ISO
Inferred from Sequence Orthology
more info
 
DNA-binding transcription activator activity, RNA polymerase II-specific ISO
Inferred from Sequence Orthology
more info
 
RNA polymerase II proximal promoter sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
RNA polymerase II regulatory region sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
protein domain specific binding ISO
Inferred from Sequence Orthology
more info
 
sequence-specific DNA binding IGI
Inferred from Genetic Interaction
more info
PubMed 
Process Evidence Code Pubs
anatomical structure formation involved in morphogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
anatomical structure morphogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
anterior/posterior pattern specification IGI
Inferred from Genetic Interaction
more info
PubMed 
embryonic skeletal system morphogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
facial nerve structural organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
facial nucleus development IMP
Inferred from Mutant Phenotype
more info
PubMed 
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
rhombomere 4 development IGI
Inferred from Genetic Interaction
more info
PubMed 
rhombomere 5 development IGI
Inferred from Genetic Interaction
more info
PubMed 
rhombomere development IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
homeobox protein Hox-B1
Names
homeo box B1
homeobox protein Hox-2.9

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008266.5NP_032292.3  homeobox protein Hox-B1

    See identical proteins and their annotated locations for NP_032292.3

    Status: VALIDATED

    Source sequence(s)
    AK017686, AW537768, BC103598, CF582524, CF582525
    Consensus CDS
    CCDS25300.1
    UniProtKB/Swiss-Prot
    P17919
    Related
    ENSMUSP00000019117.2, ENSMUST00000019117.2
    Conserved Domains (1) summary
    pfam00046
    Location:203255
    Homeobox; Homeobox domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

    Range
    96365746..96368254
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006532280.1XP_006532343.1  homeobox protein Hox-B1 isoform X1

    Conserved Domains (1) summary
    pfam00046
    Location:236288
    Homeobox; Homeobox domain
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