Hoxa6 homeobox A6 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Hoxa6provided by MGI
Official Full Name: homeobox A6provided by MGI
Primary source: MGI:MGI:96178
See related: Ensembl:ENSMUSG00000043219 Vega:OTTMUSG00000018882
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Hox-1.2
Expression: Biased expression in colon adult (RPKM 5.1), ovary adult (RPKM 3.7) and 11 other tissues See more
Orthologs: human all

Genomic context

Location:: 6 B3; 6 25.4 cM

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
106	current	GRCm38.p4 (GCF_000001635.24)	6	NC_000072.6 (52206365..52208624, complement)
Build 37.2	previous assembly	MGSCv37 (GCF_000001635.18)	6	NC_000072.5 (52156364..52158623, complement)

Chromosome 6 - NC_000072.6 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (1) 1 citation

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Hoxa6 (e-PCR), detects polymorphism
- UniSTS:143370

Hoxa6 (e-PCR), detects polymorphism
- UniSTS:536644

UniSTS:467537 (e-PCR)
- UniSTS:467537

Hoxa6 (e-PCR), detects polymorphism
- UniSTS:467537

NoName (e-PCR)
- UniSTS:492898

Hoxa6 (e-PCR), detects polymorphism
- UniSTS:547735

Homology

Homologs of the Hoxa6 gene: The Hoxa6 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, rat, chicken, and frog.
Orthologs from Annotation Pipeline: 175 organisms have orthologs with human gene Hoxa6
The Hierarchical Catalog of Orthologs

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
DNA binding	IEA Inferred from Electronic Annotation more info
DNA-binding transcription factor activity	IEA Inferred from Electronic Annotation more info
RNA polymerase II distal enhancer sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info	PubMed
sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding	IBA Inferred from Biological aspect of Ancestor more info	PubMed
transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info	PubMed

Process	Evidence Code	Pubs
anterior/posterior pattern specification	IBA Inferred from Biological aspect of Ancestor more info	PubMed
anterior/posterior pattern specification	IGI Inferred from Genetic Interaction more info	PubMed
anterior/posterior pattern specification	IMP Inferred from Mutant Phenotype more info	PubMed
embryonic skeletal system development	IGI Inferred from Genetic Interaction more info	PubMed
embryonic skeletal system morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
multicellular organism development	IEA Inferred from Electronic Annotation more info
regulation of transcription, DNA-templated	IEA Inferred from Electronic Annotation more info
transcription, DNA-templated	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
nucleus	IBA Inferred from Biological aspect of Ancestor more info	PubMed
nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: homeobox protein Hox-A6

Names: homeo box A6; homeobox protein Hox-1.2; homeobox protein M5-4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.