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Hoxa6 homeobox A6 [ Mus musculus (house mouse) ]

Gene ID: 15403, updated on 12-Jun-2025
Official Symbol
Hoxa6provided by MGI
Official Full Name
homeobox A6provided by MGI
Primary source
MGI:MGI:96178
See related
Ensembl:ENSMUSG00000043219 AllianceGenome:MGI:96178
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Hox-1.2
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within anterior/posterior pattern specification and embryonic skeletal system development. Predicted to be located in nuclear speck. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; genitourinary system; gut; limb; and vertebral cartilage condensation. Orthologous to human HOXA6 (homeobox A6). [provided by Alliance of Genome Resources, Jun 2025]
Expression
Biased expression in colon adult (RPKM 5.1), ovary adult (RPKM 3.7) and 11 other tissues See more
Orthologs
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Location:
6 B3; 6 25.4 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (52181838..52185652, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (52204858..52208672, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene homeobox A3 Neighboring gene predicted gene, 57749 Neighboring gene homeobox A4 Neighboring gene Hoxa cluster antisense RNA 3 Neighboring gene homeobox A5 Neighboring gene homeobox A7 Neighboring gene mistral long non-coding RNA Neighboring gene predicted gene, 57855 Neighboring gene homeobox A9

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
Products Interactant Other Gene Complex Source Pubs Description

Markers

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in nuclear speck IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear speck ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
homeobox protein Hox-A6
Names
homeo box A6
homeobox protein Hox-1.2
homeobox protein M5-4

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010454.3NP_034584.1  homeobox protein Hox-A6

    See identical proteins and their annotated locations for NP_034584.1

    Status: VALIDATED

    Source sequence(s)
    AC015583, BC119105, BQ558488
    Consensus CDS
    CCDS20144.1
    UniProtKB/Swiss-Prot
    P09092, Q9JI98
    UniProtKB/TrEMBL
    Q0VEU7
    Related
    ENSMUSP00000058755.8, ENSMUST00000062829.9
    Conserved Domains (1) summary
    pfam00046
    Location:158210
    Homeobox; Homeobox domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    52181838..52185652 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)