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BTNL9 butyrophilin like 9 [ Homo sapiens (human) ]

Gene ID: 153579, updated on 1-Aug-2020

Summary

Official Symbol
BTNL9provided by HGNC
Official Full Name
butyrophilin like 9provided by HGNC
Primary source
HGNC:HGNC:24176
See related
Ensembl:ENSG00000165810
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BTN3; BTN8; VDLS1900
Expression
Biased expression in fat (RPKM 71.4), lung (RPKM 16.7) and 4 other tissues See more
Orthologs

Genomic context

See BTNL9 in Genome Data Viewer
Location:
5q35.3
Exon count:
14
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (181039872..181061525)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (180467203..180488523)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene butyrophilin like 3 Neighboring gene RNA, U6 small nuclear 1036, pseudogene Neighboring gene microRNA 8089 Neighboring gene ribosomal protein L13 pseudogene 10 Neighboring gene tRNA-Val (anticodon CAC) 1-2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ99557

Gene Ontology Provided by GOA

Function Evidence Code Pubs
signaling receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
T cell receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of cytokine production IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of immune response IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
butyrophilin-like protein 9
Names
butyrophilin 3

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001308245.2NP_001295174.1  butyrophilin-like protein 9 isoform b precursor

    See identical proteins and their annotated locations for NP_001295174.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains alternate 3' exon structure, and it thus differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (b) has a distinct C-terminus and is shorter than isoform a.
    Source sequence(s)
    BC062459, DC379841
    Consensus CDS
    CCDS78104.1
    UniProtKB/Swiss-Prot
    Q6UXG8
    Related
    ENSP00000366037.2, ENST00000376841.6
    Conserved Domains (1) summary
    cd05713
    Location:52151
    Ig_MOG_like; Immunoglobulin (Ig)-like domain of myelin oligodendrocyte glycoprotein (MOG)
  2. NM_152547.5NP_689760.2  butyrophilin-like protein 9 isoform a precursor

    See identical proteins and their annotated locations for NP_689760.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
    Source sequence(s)
    AY358358, BC042112, DC379841
    Consensus CDS
    CCDS4460.2
    UniProtKB/Swiss-Prot
    Q6UXG8
    UniProtKB/TrEMBL
    Q8N324
    Related
    ENSP00000330200.9, ENST00000327705.14
    Conserved Domains (4) summary
    cd05713
    Location:52151
    Ig_MOG_like; Immunoglobulin (Ig)-like domain of myelin oligodendrocyte glycoprotein (MOG)
    smart00410
    Location:46150
    IG_like; Immunoglobulin like
    cd13733
    Location:329503
    SPRY_PRY_C-I_1; PRY/SPRY domain in tripartite motif-containing (TRIM) proteins, including TRIM5, TRIM6, TRIM7, TRIM10, TRIM11, TRIM17, TRIM20, TRIM21, TRIM27, TRIM35, TRIM38, TRIM41, TRIM50, TRIM58, TRIM60, TRIM62, TRIM69, TRIM72, NF7 and bloodthirsty
    cl21462
    Location:281317
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20200522

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    181039872..181061525
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006714825.4XP_006714888.1  butyrophilin-like protein 9 isoform X5

    See identical proteins and their annotated locations for XP_006714888.1

    Conserved Domains (4) summary
    smart00410
    Location:2481
    IG_like; Immunoglobulin like
    cd13733
    Location:260434
    SPRY_PRY_C-I_1; PRY/SPRY domain in tripartite motif-containing (TRIM) proteins, including TRIM5, TRIM6, TRIM7, TRIM10, TRIM11, TRIM17, TRIM20, TRIM21, TRIM27, TRIM35, TRIM38, TRIM41, TRIM50, TRIM58, TRIM60, TRIM62, TRIM69, TRIM72, NF7 and bloodthirsty
    cl11960
    Location:182
    Ig; Immunoglobulin domain
    cl21462
    Location:212248
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
  2. XM_024454380.1XP_024310148.1  butyrophilin-like protein 9 isoform X1

    Conserved Domains (3) summary
    cd13733
    Location:358532
    SPRY_PRY_C-I_1; PRY/SPRY domain in tripartite motif-containing (TRIM) proteins, including TRIM5, TRIM6, TRIM7, TRIM10, TRIM11, TRIM17, TRIM20, TRIM21, TRIM27, TRIM35, TRIM38, TRIM41, TRIM50, TRIM58, TRIM60, TRIM62, TRIM69, TRIM72, NF7 and bloodthirsty
    cd05713
    Location:52151
    Ig_MOG_like; Immunoglobulin (Ig)-like domain of myelin oligodendrocyte glycoprotein (MOG)
    cl21462
    Location:281317
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
  3. XM_006714824.4XP_006714887.1  butyrophilin-like protein 9 isoform X3

    Conserved Domains (3) summary
    cd05713
    Location:52151
    Ig_MOG_like; Immunoglobulin (Ig)-like domain of myelin oligodendrocyte glycoprotein (MOG)
    smart00410
    Location:46150
    IG_like; Immunoglobulin like
    cd13733
    Location:322496
    SPRY_PRY_C-I_1; PRY/SPRY domain in tripartite motif-containing (TRIM) proteins, including TRIM5, TRIM6, TRIM7, TRIM10, TRIM11, TRIM17, TRIM20, TRIM21, TRIM27, TRIM35, TRIM38, TRIM41, TRIM50, TRIM58, TRIM60, TRIM62, TRIM69, TRIM72, NF7 and bloodthirsty
  4. XM_006714823.4XP_006714886.1  butyrophilin-like protein 9 isoform X2

    Conserved Domains (3) summary
    cd05713
    Location:52151
    Ig_MOG_like; Immunoglobulin (Ig)-like domain of myelin oligodendrocyte glycoprotein (MOG)
    smart00410
    Location:46150
    IG_like; Immunoglobulin like
    cd13733
    Location:322496
    SPRY_PRY_C-I_1; PRY/SPRY domain in tripartite motif-containing (TRIM) proteins, including TRIM5, TRIM6, TRIM7, TRIM10, TRIM11, TRIM17, TRIM20, TRIM21, TRIM27, TRIM35, TRIM38, TRIM41, TRIM50, TRIM58, TRIM60, TRIM62, TRIM69, TRIM72, NF7 and bloodthirsty
  5. XM_017009113.2XP_016864602.1  butyrophilin-like protein 9 isoform X4

  6. XM_011534444.3XP_011532746.1  butyrophilin-like protein 9 isoform X6

    See identical proteins and their annotated locations for XP_011532746.1

    UniProtKB/Swiss-Prot
    Q6UXG8
    Conserved Domains (1) summary
    cd05713
    Location:52151
    Ig_MOG_like; Immunoglobulin (Ig)-like domain of myelin oligodendrocyte glycoprotein (MOG)
  7. XM_017009115.2XP_016864604.1  butyrophilin-like protein 9 isoform X7

    Related
    ENSP00000425424.1, ENST00000491209.5
  8. XM_017009114.1XP_016864603.1  butyrophilin-like protein 9 isoform X5

    Conserved Domains (4) summary
    smart00410
    Location:2481
    IG_like; Immunoglobulin like
    cd13733
    Location:260434
    SPRY_PRY_C-I_1; PRY/SPRY domain in tripartite motif-containing (TRIM) proteins, including TRIM5, TRIM6, TRIM7, TRIM10, TRIM11, TRIM17, TRIM20, TRIM21, TRIM27, TRIM35, TRIM38, TRIM41, TRIM50, TRIM58, TRIM60, TRIM62, TRIM69, TRIM72, NF7 and bloodthirsty
    cl11960
    Location:182
    Ig; Immunoglobulin domain
    cl21462
    Location:212248
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
  9. XM_017009116.1XP_016864605.1  butyrophilin-like protein 9 isoform X8

    Conserved Domains (1) summary
    cd13733
    Location:70244
    SPRY_PRY_C-I_1; PRY/SPRY domain in tripartite motif-containing (TRIM) proteins, including TRIM5, TRIM6, TRIM7, TRIM10, TRIM11, TRIM17, TRIM20, TRIM21, TRIM27, TRIM35, TRIM38, TRIM41, TRIM50, TRIM58, TRIM60, TRIM62, TRIM69, TRIM72, NF7 and bloodthirsty
  10. XM_017009117.1XP_016864606.1  butyrophilin-like protein 9 isoform X9

RNA

  1. XR_001742017.2 RNA Sequence

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