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MBLAC2 metallo-beta-lactamase domain containing 2 [ Homo sapiens (human) ]

Gene ID: 153364, updated on 13-Mar-2020

Summary

Official Symbol
MBLAC2provided by HGNC
Official Full Name
metallo-beta-lactamase domain containing 2provided by HGNC
Primary source
HGNC:HGNC:33711
See related
Ensembl:ENSG00000176055
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in brain (RPKM 4.5), ovary (RPKM 4.5) and 25 other tissues See more
Orthologs

Genomic context

See MBLAC2 in Genome Data Viewer
Location:
5q14.3
Exon count:
2
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (90458209..90474771, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (89754020..89770585, complement)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC731157 Neighboring gene centrin 3 Neighboring gene RNA polymerase III subunit G Neighboring gene LysM domain containing 3 Neighboring gene adhesion G protein-coupled receptor V1 Neighboring gene uncharacterized LOC105379077

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC46734, DKFZp686P15118

Gene Ontology Provided by GOA

Function Evidence Code Pubs
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
extracellular exosome HDA PubMed 

General protein information

Preferred Names
metallo-beta-lactamase domain-containing protein 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_203406.2NP_981951.2  metallo-beta-lactamase domain-containing protein 2

    Status: VALIDATED

    Source sequence(s)
    AC093510
    Consensus CDS
    CCDS4067.1
    Related
    ENSP00000314776.6, ENST00000316610.7
    Conserved Domains (1) summary
    cd07712
    Location:22231
    MBLAC2-like_MBL-fold; uncharacterized human metallo-beta-lactamase domain-containing protein 2 and related proteins; MBL-fold metallo hydrolase domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    90458209..90474771 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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