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Hmgn1 high mobility group nucleosomal binding domain 1 [ Mus musculus (house mouse) ]

Gene ID: 15312, updated on 8-Feb-2024

Summary

Official Symbol
Hmgn1provided by MGI
Official Full Name
high mobility group nucleosomal binding domain 1provided by MGI
Primary source
MGI:MGI:96120
See related
Ensembl:ENSMUSG00000040681 AllianceGenome:MGI:96120
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Hmg14; HMG-14
Summary
Enables chromatin binding activity. Acts upstream of or within several processes, including nucleotide-excision repair; positive regulation of NAD+ ADP-ribosyltransferase activity; and response to UV. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; sensory organ; and skin. Orthologous to human HMGN1 (high mobility group nucleosome binding domain 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E11.5 (RPKM 270.4), limb E14.5 (RPKM 161.5) and 21 other tissues See more
Orthologs
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Genomic context

See Hmgn1 in Genome Data Viewer
Location:
16 C4; 16 56.83 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (95922788..95928925, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (96121588..96127725, complement)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer mm9_chr16:96212367-96212668 Neighboring gene proteasome (prosome, macropain) assembly chaperone 1 Neighboring gene STARR-seq mESC enhancer starr_41611 Neighboring gene bromodomain and WD repeat domain containing 1 Neighboring gene STARR-seq mESC enhancer starr_41612 Neighboring gene STARR-seq mESC enhancer starr_41614 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:96307304-96307505 Neighboring gene STARR-positive B cell enhancer mm9_chr16:96331382-96331682 Neighboring gene STARR-positive B cell enhancer mm9_chr16:96349246-96349547 Neighboring gene guided entry of tail-anchored proteins factor 1 Neighboring gene Leber congenital amaurosis 5-like Neighboring gene predicted gene, 53923

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1)  1 citation
  • Endonuclease-mediated (4) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC103397

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables chromatin binding IDA
Inferred from Direct Assay
more info
PubMed 
enables nucleosomal DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
part_of chromatin IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in female germ cell nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
non-histone chromosomal protein HMG-14
Names
high mobility group nucleosome-binding domain-containing protein 1
high mobility group protein 14

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008251.3NP_032277.3  non-histone chromosomal protein HMG-14

    See identical proteins and their annotated locations for NP_032277.3

    Status: VALIDATED

    Source sequence(s)
    AK010763, BU923172
    Consensus CDS
    CCDS28353.1
    UniProtKB/Swiss-Prot
    P18608, Q5HZY9
    UniProtKB/TrEMBL
    A0A3B2W3M7
    Related
    ENSMUSP00000061012.8, ENSMUST00000050884.16
    Conserved Domains (1) summary
    pfam01101
    Location:290
    HMG14_17; HMG14 and HMG17

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    95922788..95928925 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)