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MGAT4D MGAT4 family member D [ Homo sapiens (human) ]

Gene ID: 152586, updated on 4-Oct-2020

Summary

Official Symbol
MGAT4Dprovided by HGNC
Official Full Name
MGAT4 family member Dprovided by HGNC
Primary source
HGNC:HGNC:43619
See related
Ensembl:ENSG00000205301 MIM:610310
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GnT1IP
Expression
Restricted expression toward testis (RPKM 7.0) See more
Orthologs

Genomic context

See MGAT4D in Genome Data Viewer
Location:
4q31.1
Exon count:
14
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 4 NC_000004.12 (140442257..140499046, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (141364529..141419531, complement)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene short coiled-coil protein Neighboring gene SCOC antisense RNA 1 Neighboring gene ribosomal protein L14 pseudogene 3 Neighboring gene calmegin Neighboring gene ELMO domain containing 2 Neighboring gene uncoupling protein 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

Associated conditions

Description Tests
Genome-wide association with select biomarker traits in the Framingham Heart Study.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • MGC43429

Gene Ontology Provided by GOA

Function Evidence Code Pubs
acetylglucosaminyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
cell differentiation IEA
Inferred from Electronic Annotation
more info
 
negative regulation of protein glycosylation IEA
Inferred from Electronic Annotation
more info
 
protein N-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
spermatogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
Golgi stack IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
endoplasmic reticulum-Golgi intermediate compartment IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D
Names
GlcNAcT-I Inhibitory Protein
N-acetylglucosaminyltransferase MGAT1 inhibitory protein
glycosyltransferase 54 domain containing 1
glycosyltransferase 54 domain-containing protein
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase family, member D
NP_001264282.1
XP_011529952.1
XP_011529953.1
XP_011529954.1
XP_011529955.1
XP_011529956.1
XP_011529958.1
XP_011529959.1
XP_011529960.1
XP_011529961.1
XP_011529963.1
XP_011529964.1
XP_011529965.1
XP_011529966.1
XP_011529967.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001277353.2NP_001264282.1  alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D

    See identical proteins and their annotated locations for NP_001264282.1

    Status: VALIDATED

    Source sequence(s)
    AC093671, BI826002, BI828214, DB444046, DB462368
    Consensus CDS
    CCDS64066.1
    UniProtKB/Swiss-Prot
    A6NG13
    Related
    ENSP00000421185.1, ENST00000511113.6
    Conserved Domains (1) summary
    pfam04666
    Location:96372
    Glyco_transf_54; N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p13 Primary Assembly

    Range
    140442257..140499046 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011531665.3XP_011529967.1  alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D isoform X10

    See identical proteins and their annotated locations for XP_011529967.1

    Conserved Domains (1) summary
    pfam04666
    Location:1186
    Glyco_transf_54; N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region
  2. XM_011531658.3XP_011529960.1  alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D isoform X6

    Conserved Domains (1) summary
    pfam04666
    Location:30273
    Glyco_transf_54; N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region
  3. XM_011531663.3XP_011529965.1  alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D isoform X10

    See identical proteins and their annotated locations for XP_011529965.1

    Conserved Domains (1) summary
    pfam04666
    Location:1186
    Glyco_transf_54; N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region
  4. XM_011531656.3XP_011529958.1  alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D isoform X4

    Conserved Domains (1) summary
    pfam04666
    Location:85326
    Glyco_transf_54; N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region
  5. XM_011531654.3XP_011529956.1  alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D isoform X3

    Conserved Domains (1) summary
    pfam04666
    Location:96353
    Glyco_transf_54; N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region
  6. XM_011531650.3XP_011529952.1  alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D isoform X1

    Conserved Domains (1) summary
    pfam04666
    Location:96362
    Glyco_transf_54; N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region
  7. XM_011531652.2XP_011529954.1  alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D isoform X2

    See identical proteins and their annotated locations for XP_011529954.1

    Conserved Domains (1) summary
    pfam04666
    Location:80356
    Glyco_transf_54; N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region
  8. XM_011531653.3XP_011529955.1  alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D isoform X2

    See identical proteins and their annotated locations for XP_011529955.1

    Conserved Domains (1) summary
    pfam04666
    Location:80356
    Glyco_transf_54; N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region
  9. XM_011531651.2XP_011529953.1  alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D isoform X2

    See identical proteins and their annotated locations for XP_011529953.1

    Conserved Domains (1) summary
    pfam04666
    Location:80356
    Glyco_transf_54; N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region
  10. XM_011531664.2XP_011529966.1  alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D isoform X10

    See identical proteins and their annotated locations for XP_011529966.1

    Conserved Domains (1) summary
    pfam04666
    Location:1186
    Glyco_transf_54; N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region
  11. XM_011531657.3XP_011529959.1  alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D isoform X5

    Conserved Domains (1) summary
    pfam04666
    Location:48324
    Glyco_transf_54; N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region
  12. XM_011531659.2XP_011529961.1  alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D isoform X7

    Conserved Domains (1) summary
    pfam04666
    Location:96254
    Glyco_transf_54; N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region
  13. XM_011531661.2XP_011529963.1  alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D isoform X8

    Conserved Domains (1) summary
    pfam04666
    Location:96218
    Glyco_transf_54; N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region
  14. XM_011531662.2XP_011529964.1  alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D isoform X9

    Conserved Domains (1) summary
    pfam04666
    Location:96191
    Glyco_transf_54; N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region

RNA

  1. XR_938697.2 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001034840.1: Suppressed sequence

    Description
    NM_001034840.1: This RefSeq was permanently suppressed because it is a partial sequence.
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