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SLC66A1L solute carrier family 66 member 1 like [ Homo sapiens (human) ]

Gene ID: 152078, updated on 22-Sep-2022

Summary

Official Symbol
SLC66A1Lprovided by HGNC
Official Full Name
solute carrier family 66 member 1 likeprovided by HGNC
Primary source
HGNC:HGNC:25146
See related
Ensembl:ENSG00000174899 AllianceGenome:HGNC:25146
Gene type
pseudo
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PQLC2L; C3orf55; SLC66A2L
Summary
Predicted to enable L-arginine transmembrane transporter activity and L-lysine transmembrane transporter activity. Predicted to be involved in L-arginine transmembrane transport and L-lysine transmembrane transport. Predicted to be active in lysosomal membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in fat (RPKM 5.2), thyroid (RPKM 2.0) and 4 other tissues See more
Orthologs
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Genomic context

See SLC66A1L in Genome Data Viewer
Location:
3q25.32
Exon count:
7
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (157543312..157601094)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (160317934..160375697)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (157261101..157318883)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene ventricular zone expressed PH domain containing 1 Neighboring gene pentraxin 3 Neighboring gene CRISPRi-validated cis-regulatory element chr3.4666 Neighboring gene VISTA enhancer hs638 Neighboring gene RN7SK pseudogene 46

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Other Names

  • PQ loop repeat containing 2 like
  • PQ-loop repeat-containing protein 2-like

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables L-lysine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables basic amino acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in L-lysine transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in basic amino acid transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in lysosomal membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_024016.3 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) includes an alternate exon in the 3' end, compared to variant 1. The transcript is sufficiently abundant to represent as a RefSeq record; however, the predicted protein is not represented because the product is significantly truncated.
    Source sequence(s)
    AC084212, AI377021, BE905784, BX113701
    Related
    ENST00000468043.7
  2. NR_166162.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC084212
    Related
    ENST00000651329.1
  3. NR_166163.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC084212
    Related
    ENST00000651011.1
  4. NR_166164.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC084212
    Related
    ENST00000651325.1

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    157543312..157601094
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    160317934..160375697
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001099777.3: Suppressed sequence

    Description
    NM_001099777.3: This RefSeq was removed because it is now thought that this gene is a pseudogene.
  2. NM_001130001.2: Suppressed sequence

    Description
    NM_001130001.2: This RefSeq was removed because it is now thought that this gene is a pseudogene.
  3. NM_001130002.2: Suppressed sequence

    Description
    NM_001130002.2: This RefSeq was removed because it is now thought that this gene is a pseudogene.
  4. NM_001243729.1: Suppressed sequence

    Description
    NM_001243729.1: This RefSeq was removed because it is now thought that this gene is a pseudogene.