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MSL3B MSL complex subunit 3B [ Homo sapiens (human) ]

Gene ID: 151507, updated on 31-Jan-2024


Official Symbol
MSL3Bprovided by HGNC
Official Full Name
MSL complex subunit 3Bprovided by HGNC
Primary source
See related
Ensembl:ENSG00000293137 AllianceGenome:HGNC:17837
Gene type
protein coding
RefSeq status
Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Predicted to be involved in heterochromatin assembly and histone modification. Predicted to be part of MSL complex and NuA4 histone acetyltransferase complex. [provided by Alliance of Genome Resources, Apr 2022]
Biased expression in testis (RPKM 23.6), prostate (RPKM 2.5) and 10 other tissues See more
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Genomic context

Exon count:
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (233865437..233868409, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (234354240..234357213, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (234774083..234777055, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene maestro heat like repeat family member 2A Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:234731477-234731977 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:234759038-234759538 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:234763063-234764055 Neighboring gene Holliday junction recognition protein Neighboring gene transient receptor potential cation channel subfamily M member 8 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr2:234882993-234884192 Neighboring gene Sharpr-MPRA regulatory region 7512 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17351 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:234920120-234920398 Neighboring gene secreted phosphoprotein 2

Genomic regions, transcripts, and products


  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018


Products Interactant Other Gene Complex Source Pubs Description

General gene information


Clone Names

  • FLJ79271

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in chromatin organization IEA
Inferred from Electronic Annotation
more info
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
Component Evidence Code Pubs
part_of MSL complex IBA
Inferred from Biological aspect of Ancestor
more info
part_of NuA4 histone acetyltransferase complex IBA
Inferred from Biological aspect of Ancestor
more info
located_in nucleus IEA
Inferred from Electronic Annotation
more info

General protein information

Preferred Names
putative male-specific lethal-3 protein-like 2
MSL complex subunit 3 pseudogene 1
MSL3-like 2
male-specific lethal 3 homolog pseudogene 1
male-specific lethal 3-like 2
male-specific lethal-3 homolog 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001425333.1NP_001412262.1  putative male-specific lethal-3 protein-like 2

    Status: REVIEWED

    Source sequence(s)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly


  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    233865437..233868409 complement
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0


  1. NC_060926.1 Alternate T2T-CHM13v2.0

    234354240..234357213 complement
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001166217.1: Suppressed sequence

    NM_001166217.1: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
  2. NR_024322.1: Suppressed sequence

    NR_024322.1: This RefSeq was removed because it is now thought that this gene does encode a protein.